DAFTAR ISI
PENDAHULUAN --------------------------------------------------------------------------------
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DAFTAR ISI --------------------------------------------------------------------------------------
ii
DAFTAR TABEL -------------------------------------------------------------------------------
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DAFTAR GAMBAR ----------------------------------------------------------------------------
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MODUL 1 Kelainan Pada Bibir -------------------------------------------------------------------------------
1
1. Pendahuluan ------------------------------------------------------------------------------------
1
2. Relevansi ----------------------------------------------------------------------------------------
1
3. Tujuan Pembelajaran Khusus -----------------------------------------------------------------
1
4. Kegiatan Belajar --------------------------------------------------------------------------------
1
4.1. Kelainan Cacat Bawaan -----------------------------------------------------------------
1
4.1.1. Sumbing Bibir ---------------------------------------------------------------------
1
4.1.2. Cheilognathoschisis --------------------------------------------------------------
2
4.1.3. Sumbing Palatum -----------------------------------------------------------------
2
4.1.4. Cheilognathopalatoschisis ------------------------------------------------------
2
4.1.5. Obique Facial Cleft --------------------------------------------------------------
3
4.1.6. Transverse Facial Cleft ----------------------------------------------------------
3
4.2. Radang -------------------------------------------------------------------------------------
3
4.2.1. Cheilitis Vesikularis --------------------------------------------------------------
3
4.2.2. Cheilosis ---------------------------------------------------------------------------
3
4.2.3. Radang Kronis Tidak Spesifik --------------------------------------------------
3
ii
4.2.4. Radang Kronis Spesifik ----------------------------------------------------------
4
4.3. Tumor --------------------------------------------------------------------------------------
5
4.3.1. Tumor Jinak -----------------------------------------------------------------------
5
4.3.2. Pseudo Tumor ---------------------------------------------------------------------
5
4.3.2.1. Keratoacanthoma -------------------------------------------------------
6
4.3.2.2. Granuloma Pyogenicum -----------------------------------------------
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4.3.2.3. Verruform Xanthoma ---------------------------------------------------
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4.3.3. Tumor Ganas ----------------------------------------------------------------------
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4.3.3.1. Pendahuluan -------------------------------------------------------------
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4.3.3.2. Definisi -------------------------------------------------------------------
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4.3.3.3. Etiologi -------------------------------------------------------------------
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4.3.3.4. Gambaran Klinis --------------------------------------------------------
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4.3.3.5. Gambaran Histopatologis ----------------------------------------------
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4.3.3.6. Lokasi dan Insidensi ----------------------------------------------------
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4.3.3.7. Metastasis ----------------------------------------------------------------
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4.3.3.8. Diagnosis -----------------------------------------------------------------
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4.3.3.9. Diferensial Diagnosa ---------------------------------------------------
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4.3.3.10. Stadium ------------------------------------------------------------------
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4.3.3.11. Prognosa ----------------------------------------------------------------
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4.3.3.12. Terapi --------------------------------------------------------------------
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5. Rangkuman -------------------------------------------------------------------------------------
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6. Daftar Pustaka ----------------------------------------------------------------------------------
20
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MODUL 2 Kelainan Pada Mukosa Mulut -------------------------------------------------------------------
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1. Pendahuluan ------------------------------------------------------------------------------------
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2. Relevansi ----------------------------------------------------------------------------------------
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3. Tujuan Pembelajaran Khusus -----------------------------------------------------------------
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4. Kegiatan Belajar --------------------------------------------------------------------------------
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4.1. Radang -------------------------------------------------------------------------------------
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4.1.1. Ginggivo-Stomatitis Herpetika Acuta -----------------------------------------
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4.1.2. Stomatitis Acuta Fibronosa -----------------------------------------------------
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4.1.3. Ginggivitis Ulcerative Nekroticans --------------------------------------------
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4.1.4. Angina Ludwig --------------------------------------------------------------------
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4.1.5. Stomatitis Acuta Catarrhalis-----------------------------------------------------
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4.1.6. Stomatitis Nicotina ---------------------------------------------------------------
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4.1.7. Stomatitis Aphtosa ----------------------------------------------------------------
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4.2. Pigmentasi ---------------------------------------------------------------------------------
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4.2.1. Tatto Amalgam --------------------------------------------------------------------
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4.2.2. Argyria -----------------------------------------------------------------------------
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4.2.3. Plumbism ---------------------------------------------------------------------------
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4.2.4. Melanosis --------------------------------------------------------------------------
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4.3. Tumor Jinak -------------------------------------------------------------------------------
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4.3.1. Papiloma ---------------------------------------------------------------------------
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4.3.2. Fibroma ----------------------------------------------------------------------------
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4.3.3. Lipoma -----------------------------------------------------------------------------
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4.3.4. Hemangioma ----------------------------------------------------------------------
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4.3.5. Limfangioma ----------------------------------------------------------------------
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4.3.6. Neurofibroma ---------------------------------------------------------------------
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4.3.7. Rhabdomyoma ---------------------------------------------------------------------
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4.3.7.1. Pendahuluan -------------------------------------------------------------
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4.3.3.2. Klasifikasi-----------------------------------------------------------------
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4.4. Epulis --------------------------------------------------------------------------------------
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4.4.1. Epulis Granulomatosa -----------------------------------------------------------
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4.4.2. Epulis Angiomatosa --------------------------------------------------------------
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4.4.3. Epulis Fibromatosa ---------------------------------------------------------------
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4.4.3. Epulis Gigantocellulare ----------------------------------------------------------
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4.4.5. Epulis Fissuratum ----------------------------------------------------------------
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4.4.6. Epulis Gravidarum ---------------------------------------------------------------
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5. Rangkuman -------------------------------------------------------------------------------------
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6. Daftar Pustaka ----------------------------------------------------------------------------------
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MODUL 3 Kelainan Pada Lidah ------------------------------------------------------------------------------
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1. Pendahuluan ------------------------------------------------------------------------------------
45
2. Relevansi ----------------------------------------------------------------------------------------
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3. Tujuan Pembelajaran Khusus -----------------------------------------------------------------
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4. Kegiatan Belajar --------------------------------------------------------------------------------
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4.1. Kelainan Kongenital ---------------------------------------------------------------------
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4.1.1. Mikroglosia ------------------------------------------------------------------------
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4.1.2. Makroglosia -----------------------------------------------------------------------
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4.1.3. Lingual Thyroid -------------------------------------------------------------------
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4.1.4. Median Rhomboid Glossitis -----------------------------------------------------
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4.1.5. Bifid Tongue------------------------------------------------------------------------
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4.2. Radang -------------------------------------------------------------------------------------
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4.2.1. Radang Akut -----------------------------------------------------------------------
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4.2.1.1. Glossitis Akuta -----------------------------------------------------------
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4.2.1.2. Stomatitis Scarlanita ----------------------------------------------------
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4.2.2. Radang Khronis Spesifik --------------------------------------------------------
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4.2.2.1. Tuberculosis -------------------------------------------------------------
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4.2.2.2. Sifilis ----------------------------------------------------------------------
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4.2.3. Radang Kronis Yang Tidak Spesifik -------------------------------------------
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4.2.3.1. Geographic Tounge -----------------------------------------------------
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4.2.3.2. Hairy Tounge ------------------------------------------------------------
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4.3. Lesi-lesi Prekanker -----------------------------------------------------------------------
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4.3.1. Leukoplakia ------------------------------------------------------------------------
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4.3.2. Erythroplakia ----------------------------------------------------------------------
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4.3.3. Karsinoma In Situ ----------------------------------------------------------------
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4.4. Lesi-lesi yang Lain -----------------------------------------------------------------------
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4.4.1. Lichen Planus ---------------------------------------------------------------------
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4.4.2. Nevus Pigmentosus ---------------------------------------------------------------
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4.5. Neoplasma ---------------------------------------------------------------------------------
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4.5.1. Pendahuluan -----------------------------------------------------------------------
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4.5.2. Tipe-tipe Rhabdomiosarkoma --------------------------------------------------
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4.5.3. Sistem Staging --------------------------------------------------------------------
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4.5.4. Prognosis ---------------------------------------------------------------------------
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4.5.5. Perawatan --------------------------------------------------------------------------
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4.2.3.1. Tindakan Pembedahan -------------------------------------------------
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4.2.3.2. Terapi Radiasi -----------------------------------------------------------
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5. Rangkuman -------------------------------------------------------------------------------------
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6. Daftar Pustaka ----------------------------------------------------------------------------------
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MODUL 4 Kelainan Pada Gigi dan Tulang Rahang -------------------------------------------------------
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1. Pendahuluan ------------------------------------------------------------------------------------
75
2. Relevansi ----------------------------------------------------------------------------------------
75
3. Tujuan Pembelajaran Khusus -----------------------------------------------------------------
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4. Kegiatan Belajar --------------------------------------------------------------------------------
75
4.1. Patogenesis Kelainan Cacat Bawaan --------------------------------------------------
75
4.1.1. Dentinogenesis Imperfecta ------------------------------------------------------
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4.1.2. Amelogenesis Imperfecta --------------------------------------------------------
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4.1.3. Hipoplasia Email -----------------------------------------------------------------
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4.1.4. Anodontia --------------------------------------------------------------------------
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4.1.5. Microdontia ------------------------------------------------------------------------
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4.1.6. Macrodontia -----------------------------------------------------------------------
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4.1.7. Agnathia ----------------------------------------------------------------------------
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4.1.8. Micrognathia ----------------------------------------------------------------------
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4.1.9. Macrognathia ---------------------------------------------------------------------
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4.1.10. Acromegalia ---------------------------------------------------------------------
79
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5. Rangkuman -------------------------------------------------------------------------------------
101
6. Daftar Pustaka ----------------------------------------------------------------------------------
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MODUL 5 Kelainan Pada Lidah ------------------------------------------------------------------------------
102
1. Pendahuluan ------------------------------------------------------------------------------------
102
2. Relevansi ----------------------------------------------------------------------------------------
102
3. Tujuan Pembelajaran Khusus -----------------------------------------------------------------
102
4. Kegiatan Belajar --------------------------------------------------------------------------------
102
4.1. Sialadenitis --------------------------------------------------------------------------------
103
4.2. Mucocele ----------------------------------------------------------------------------------
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4.3. Mikulicz’s Disease -----------------------------------------------------------------------
105
4.4. Mikulicz’s Syndrome ---------------------------------------------------------------------
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4.5. Sjogren Syndrome ------------------------------------------------------------------------
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4.6. Tumor Jinak Kelenjar Ludah -----------------------------------------------------------
106
4.6.1. Pendahuluan -----------------------------------------------------------------------
106
4.6.2. Patogenesis ------------------------------------------------------------------------
107
4.6.3. Klasifikasi Tumor Jinak Kelenjar Ludah --------------------------------------
109
4.6.3.1. Pleomorfik Adenoma ---------------------------------------------------
109
4.6.3.2. Monomorfik Adenoma --------------------------------------------------
111
4.6.3.3. Ductal Papiloma --------------------------------------------------------
120
4.7. Tumor Ganas Kelenjar Ludah ----------------------------------------------------------
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4.7.1. Pendahuluan -----------------------------------------------------------------------
122
4.7.2. Klasifikasi -------------------------------------------------------------------------
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5. Rangkuman -------------------------------------------------------------------------------------
129
6. Daftar Pustaka ----------------------------------------------------------------------------------
130
MODUL 6 Cara Pengambilan, Pengiriman dan Dasar Penilaian Biopsi/ Sitologi --------------------
131
1. Pendahuluan ------------------------------------------------------------------------------------
131
2. Relevansi ----------------------------------------------------------------------------------------
131
3. Tujuan Pembelajaran Khusus -----------------------------------------------------------------
131
4. Kegiatan Belajar --------------------------------------------------------------------------------
131
4.1. Prinsip Dasar Fiksasi --------------------------------------------------------------------
131
4.2. Macam-Macam Cairan Fiksasi ---------------------------------------------------------
132
4.3. Cara Pengiriman Sediaan Biopsi -------------------------------------------------------
135
4.4. Cara Pengiriman Sediaan Sitologi -----------------------------------------------------
135
4.5. Pengelolaan Jaringan --------------------------------------------------------------------
136
4.6. Interpretasi Hasil Pemeriksaan Biopsi ------------------------------------------------
140
4.7. Interpretasi Hasil Pemeriksaan Sitologis ----------------------------------------------
140
4.8. Klasifikasi Diagnosa Sitologi -----------------------------------------------------------
141
5. Rangkuman -------------------------------------------------------------------------------------
141
6. Daftar Pustaka ----------------------------------------------------------------------------------
142
LATIHAN PENGUASAAN DAN PENERAPAN TEORI ------------------------------
143
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DAFTAR TABEL
Tabel 1.1. Faktor Penyebab Karsinoma Sel Squamous --------------------------------------
10
Tabel 1.2. TNM Untuk Malignansi Pada Tumor Rongga Mulut ---------------------------
16
Tabel 1.3. Stadium Untuk Karsinoma Rongga Mulut ---------------------------------------
17
Tabel 2.1. Gambaran Klinis Variasi Klasifikasi Rhabdomyoma ---------------------------
36
Tabel 3.1. Sistem Pengelompokan Menurut Intergroup Rhabdomyosarcoma Study Group (IRS) --------------------------------------------------------------------
66
Tabel 3.2. Sistem Staging dengan G-TNM ----------------------------------------------------
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Tabel 3.3. Pengelompokan Stadium dan Angka Bertahan Hidup --------------------------
69
Tabel 6.1. Klasifikasi Diagnosa Sitologis -----------------------------------------------------
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DAFTAR GAMBAR
Gambar 1.1. Gambaran Klinis Moniliasis pada Bibir ---------------------------------------
4
Gambar 1.2. Gambaran Klinis dan Histopatologis Granuloma Pyogenicum Pada bibir ---------------------------------------------------------------------------
7
Gambar 1.3. Karsinoma Sel Squamous Pada Bibir dan Lidah ------------------------------
11
Gambar 1.4. Gambaran Histopatologis karsinoma Sel Squamous Well Differentiated ----------------------------------------------------------------
13
Gambar 2.1. Gambaran Klinis dan Histopatologis Stomatitis Nikotina -------------------
24
Gambar 2.2 Gambaran Histopatologis Tubercle Pada Tuberculosis ----------------------
25
Gambar 2.3. Gambaran Klinis Tatoo Amalgam ----------------------------------------------
26
Gambar 2.4. Gambaran Histopatologis Tatto Amalgam ------------------------------------
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Gambar 2.5. Gambaran Klinis Papiloma Pada Lidah ----------------------------------------
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Gambar 2.6. Gambaran Histopatologis Papiloma --------------------------------------------
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Gambar 2.7. Gambaran Klinis Fibroma Rongga Mulut -------------------------------------
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Gambar 2.8. Gambaran Histopathologis Fibroma --------------------------------------------
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Gambar 2.9. Gambaran Klinis Lipoma Rongga Mulut --------------------------------------
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Gambar 2.10. Gambaran Histologis Lipoma --------------------------------------------------
31
Gambar 2.11. Gambaran Klinis Hemangioma ------------------------------------------------
`32
Gambar 2.12. Gambaran Histopatologis Hemangioma Cavernosum dan Hemangioma Capilare ----------------------------------------------------
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Gambar 2.13. Gambaran Klinis dan Histopatologis Limfangioma ------------------------
34
Gambar 2.14. Gambaran Klinis Epulis Pada Gusi -------------------------------------------
40
Gambar 2.15. Gambaran Histopatologis Epulis Granulomatosa --------------------------
41
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Gambar 2.16. Gambaran Histopatologis Giant Cell Epulis ---------------------------------
42
Gambar 2.17. Gambaran Klinis Epulis Fissuratum ------------------------------------------
43
Gambar 3.1. Gambaran Klinis Median Rhomboid Glossitis --------------------------------
47
Gambar 3.2. Gambaran Histopatologis Median Rhomboid Glossitis ---------------------
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Gambar 3.3. Gambaran Klinis Leukoplakia Pada Lidah dan Mukosa Bukal -------------
54
Gambar 3.4. Gambaran Histopatologis Leukloplakia ----------------------------------------
56
Gambar 3.5. Gambaran Klinis Erythroplakia yang Bercampur dengan Leukoplakia ---------------------------------------------------------------
57
Gambar 3.6. Gambaran Klinis Lichen Planus, Reticular Form dan Hyperthropyform -------------------------------------------------------------
59
Gambar 4.1. Gambaran Klinis Ameloblastoma -----------------------------------------------
83
Gambar 4.2. Gambaran Histopatologis Ameloblastoma Tipe Follikeler ------------------
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Gambar 4.3. Gambaran Histopatologis Ameloblastoma Tipe Plexiform ------------------
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Gambar 4.4. Gambaran Histopatologis Ameloblastoma Tipe Akantomatous ------------
85
Gambar 4.5. Gambaran Klinis Torus Palatinus ----------------------------------------------
99
Gambar 4.6. Gambaran Klinis Torus Mandibularis -----------------------------------------
99
Gambar 4.7. Gambaran Mikroskopis Oswteogenic Sarcoma -------------------------------
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Gambar 5.1. Gambaran Klinis dan Histopatologis Mucocele ------------------------------
105
Gambar 5.2. Gambaran Klinis Pleomorfik Adenoma Kelenjar Parotis --------------------
110
Gambar 5.3. Gambaran Histopatologis Pleomorfik Adenoma ------------------------------
111
Gambar 5.4. Gambaran Histopatologis Onkositoma -----------------------------------------
111
Gambar 5.5. Gambaran Klinis Tumor Warthin Pasda Kelenjar Parotis -------------------
119
Gambar 5.6. Gambaran Histopatologis Tumor Warthin -------------------------------------
120
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Gambar 5.7. Gambaran Histopatologis Mucoepidermoid Carcinoma Low Grade Malignancy ---------------------------------------------------------
125
Gambar 5.8. Gambaran Histopatologis Adenoid Cystic Carcinoma -----------------------
126
Gambar 5.9. Gambaran Histopatologis Acinic Cell Carcinoma ----------------------------
127
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