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Markum A, Ismael S, Alatas H, Akib A, Firmansyah A and Sastroasmoro S. Buku ajar ilmu kesehatan anak. Jilid I Bagian Ilmu Kesehatan Anak Fakultas Kedokteran Universitas Indonesia Jakarta. 1991.
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Sheth RD. Neonatal Seizure. Medscape. 2013.
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L Hellstrom-Westas IA-W, J Agren, K Kallen. Incidence and risk factors for neonatal seizure in Sweden. Archives of Disease in Childhood. 2008; 93.
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Alberto Verrotti GL, Paola Cicioni, Claudio De Felice. New Trends in Neonatal Seizures. Journal of Pediatric Neurology. 2004.
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Hannah C. Glass TNP, Beate Danielsen, Dena Towner, David Glidden, Yvonne W. Wu. Antenatal and Intrapartum Risk Factors for Seizure in Term Newborn: A Population-based Study, California 1998-2002. Journal of Pediatric Neurology. 2009; 154.
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Jensen FE. Neonatal seizures: an update on mechanisms and management. Clinics in perinatology. 2009; 36: 881.
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Prawirohardjo S. Ilmu kandungan. Yayasan Bina Pustaka Jakarta. 2002.
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Lampiran 3. Biodata Penulis Nama
: Atika Nurmalitasari
NIM
: 22010110130162
Tempat/Tanggal lahir : Yogyakarta/30 Maret 1992 Jenis Kelamin
: Perempuan
Alamat
: Jalan Bukit Unggul I nomor 15 Sampangan, Semarang
Nomor Telepon/HP
: (024) 8317987/081215575792
Email
:
[email protected]
RIWAYAT PENDIDIKAN FORMAL 1. TK : TK Hj ISRIATI SEMARANG 1996-1998 2. SD : SD Hj ISRIATI SEMARANG 1998-2004 3. SMP : SMPN 5 SEMARANG Lulus Tahun: 2007 4. SMA : SMAN 3 SEMAANG Lulus Tahun: 2010 5. FK UNDIP : Masuk Tahun : 2010 KEANGGOTAAN ORGANISASI 1. PASKIBRA SD Hj ISRIATI 2002-2004 2. PASKIBRA SMPN 5 2005-2007 3. OSIS SMPN 5 2006-2007 4. OSIS SMAN 3 2008-2009 5. CEMETI SMAN 3 2008-2009 6. BEM FK UNDIP Departemen Seni dan Olahraga 2010
54
Lampiran 4. Hasil Pengolahan SPSS KARAKTERISTIK IBU a.
Umur ibu (tahun)
Kelompok kasus N
Valid Missing
60 60 28,40 27,00 6,132 37,600 ,991 ,309 1,145 ,608 19 48
Mean Median Std. Deviation Variance Skewness Std. Error of Skewness Kurtosis Std. Error of Kurtosis Minimum Maximum
Kelompok kontrol N
Valid Missing
60 60 25,22 23,00 5,205 27,088 1,288 ,309 1,233 ,608 17 42
Mean Median Std. Deviation Variance Skewness Std. Error of Skewness Kurtosis Std. Error of Kurtosis Minimum Maximum
Tests of Normality Kolmogorov-Smirnov(a) Statistic df Sig. umur ibu ,150 120 ,000 a Lilliefors Significance Correction
Shapiro-Wilk Statistic df ,907 120
Sig. ,000
55
Mann-Whitney Test
Test Statistics(a) Umur ibu Mann-Whitney U
239.500
Wilcoxon W
539.500
Z
-1.003
Asymp. Sig. (2-tailed)
.003
Grouping Variable: kejang neonatus
B.
Penyakit Kehamilan penyakit kehamilan (kelompok kasus)
Valid tidak ya Total
Frequency 60 54 6 120
Percent 50,0 45,0 5,0 100,0
Cumulative Percent 50,0 95,0 100,0
Valid Percent 50,0 45,0 5,0 100,0
penyakit kehamilan (kelompok kontrol)
Frequency 60
Percent 50,0
Valid Percent 50,0
Cumulative Percent 50,0
Tidak
60
50,0
50,0
100,0
Total
120
100,0
100,0
Valid
Chi-Square Tests
Pearson Chi-Square Likelihood Ratio N of Valid Cases
Value 120,000(a) 166,355 120
Df 2 2
Asymp. Sig. (2sided) ,365 ,000
56
KARAKTERISTIK NEONATUS
a. Berat lahir (gram) Kelompok kasus N
Valid Missing
60 60 2897,00 2980,00 417,459 174272,20 3 -,147 ,309 ,467 ,608 1800 3900
Valid Missing
60 60 3083,17 3000,00 479,178 229611,83 6 1,087 ,309 2,980 ,608 2200 5000
Mean Median Std. Deviation Variance Skewness Std. Error of Skewness Kurtosis Std. Error of Kurtosis Minimum Maximum
Kelompok kontrol N Mean Median Std. Deviation Variance Skewness Std. Error of Skewness Kurtosis Std. Error of Kurtosis Minimum Maximum
Tests of Normality Kolmogorov-Smirnov(a) Statistic ,147 a Lilliefors Significance Correction berat lahir
df 120
Sig. ,000
Shapiro-Wilk Statistic ,957
df 120
Sig. ,001
57
Mann-Whitney Test
Test Statistics(a) berat lahir Mann-Whitney U
261.000 561.000 -.560
Wilcoxon W Z Asymp. Sig. (2-tailed)
.025
a Grouping Variable: kejang neonatus
b. Jenis kelamin Case Processing Summary Cases Valid N JK kontrol * JK kasus
60
Missing Percent 100,0%
N 0
Total
Percent ,0%
N 60
JK kontrol * JK kasus Crosstabulation JK kasus 1 JK kontrol
LAKI-LAKI
Count Expected Count
PEREMPUAN
Count Expected Count Count
Total
Expected Count
Total 2
1
33
16
49
35,1
13,9
49,0
10 7,9
1 3,1
11 11,0
43 43,0
17 17,0
60 60,0
Chi-Square Tests
Pearson Chi-Square Continuity Correction(a) Likelihood Ratio
Value 2,456(b) 1,433
1
Asymp. Sig. (2-sided) ,195
1
,231
df
Exact Sig. (2-sided)
Exact Sig. (1-sided)
2,921 1 ,087 Fisher's Exact Test ,155 N of Valid Cases 60 a Computed only for a 2x2 table b 1 cells (25,0%) have expected count less than 5. The minimum expected count is 3,12
,112
Percent 100,0%
58
FREKUENSI SUBJEK PENELITIAN Kelompok
Valid
Frequency 60 60 120
Kasus Kontrol Total
Percent 50,0 50,0 100,0
Cumulat iv e Percent 50,0 100,0
Valid Percent 50,0 50,0 100,0
Infeksi IU
Valid
Ya Tidak Total
Frequency 10 110 120
Percent 8,3 91,7 100,0
Valid Percent 8,3 91,7 100,0
Cumulat iv e Percent 8,3 100,0
Status paritas
Valid
primipara multipara Total
Frequency 65 55 120
Percent 54,2 45,8 100,0
Valid Percent 54,2 45,8 100,0
Cumulat iv e Percent 54,2 100,0
cara. persal inan
Valid
SC Perv aginam Total
Frequency 31 89 120
Percent 25,8 74,2 100,0
Valid Percent 25,8 74,2 100,0
Cumulativ e Percent 25,8 100,0
Gawat janin
Valid
Ya Tidak Total
Frequency 24 96 120
Percent 20,0 80,0 100,0
Valid Percent 20,0 80,0 100,0
Cumulat iv e Percent 20,0 100,0
59
Resusitasi
Valid
Ya Tidak Total
Frequency 37 83 120
Percent 30,8 69,2 100,0
Valid Percent 30,8 69,2 100,0
Cumulat iv e Percent 30,8 100,0
Masa gestasi
Valid
preterm aterm Total
Frequency 14 106 120
Percent 11,7 88,3 100,0
Valid Percent 11,7 88,3 100,0
Cumulat iv e Percent 11,7 100,0
HASIL ANALISIS FAKTOR-FAKTOR YANG BERPENGARUH
A. Infeksi intrauterin Crosstab
Inf eksi IU
Ya
Tidak
Total
Count Expected Count % wit hin Kelompok % of Total Count Expected Count % wit hin Kelompok % of Total Count Expected Count % wit hin Kelompok % of Total
Kelompok Kasus Kontrol 9 1 5,0 5,0 15,0% 1,7% 7,5% ,8% 51 59 55,0 55,0 85,0% 98,3% 42,5% 49,2% 60 60 60,0 60,0 100,0% 100,0% 50,0% 50,0%
Total 10 10,0 8,3% 8,3% 110 110,0 91,7% 91,7% 120 120,0 100,0% 100,0%
60
Chi-Square Tests
Pearson Chi-Square Continuity Correctiona Likelihood Ratio Fisher's Exact Test Linear-by -Linear Association N of Valid Cases
Value 6,982b 5,345 7,944
6,924
df 1 1 1
Asy mp. Sig. (2-sided) ,008 ,021 ,005
1
Exact Sig. (2-sided)
Exact Sig. (1-sided)
,017
,008
,009
120
a. Computed only f or a 2x2 table b. 0 cells (,0%) hav e expected count less than 5. The minimum expected count is 5,00.
Risk Esti mate
Value Odds Rat io f or Inf eksi I U (Ya / Tidak) For cohort Kelompok = Kasus For cohort Kelompok = Kont rol N of Valid Cases
95% Conf idence Interv al Lower Upper
10,412
1,275
84,998
1,941
1,455
2,590
,186
,029
1,207
120
61
B. Status paritas Chi-Square Tests Value ,034b ,000 ,034
Pearson Chi-Square Continuity Correctiona Likelihood Ratio Fisher's Exact Test Linear-by -Linear Association N of Valid Cases
Asy mp. Sig. (2-sided) ,855 1,000 ,855
df 1 1 1
,033
1
Exact Sig. (2-sided)
Exact Sig. (1-sided)
1,000
,500
,855
120
a. Computed only f or a 2x2 table b. 0 cells (,0%) hav e expected count less than 5. The minimum expected count is 27,50.
Crosstab
St at us paritas
primipara
multipara
Total
Count Expected Count % wit hin Kelompok % of Total Count Expected Count % wit hin Kelompok % of Total Count Expected Count % wit hin Kelompok % of Total
Risk Esti mate
Value Odds Rat io f or Status paritas (primipara / multipara) For cohort Kelompok = Kasus For cohort Kelompok = Kont rol N of Valid Cases
95% Conf idence Interv al Lower Upper
,935
,456
1,918
,967
,676
1,384
1,034
,721
1,483
120
Kelompok Kasus Kontrol 32 33 32,5 32,5 53,3% 55,0% 26,7% 27,5% 28 27 27,5 27,5 46,7% 45,0% 23,3% 22,5% 60 60 60,0 60,0 100,0% 100,0% 50,0% 50,0%
Total 65 65,0 54,2% 54,2% 55 55,0 45,8% 45,8% 120 120,0 100,0% 100,0%
62
C. Cara Persalinan Crosstab
cara.persalinan
SC
Perv aginam
Total
Kelompok Kasus Kontrol 18 13 15,5 15,5 30,0% 21,7% 15,0% 10,8% 42 47 44,5 44,5 70,0% 78,3% 35,0% 39,2% 60 60 60,0 60,0 100,0% 100,0% 50,0% 50,0%
Count Expected Count % wit hin Kelompok % of Total Count Expected Count % wit hin Kelompok % of Total Count Expected Count % wit hin Kelompok % of Total
Total 31 31,0 25,8% 25,8% 89 89,0 74,2% 74,2% 120 120,0 100,0% 100,0%
Chi-Square Tests
Pearson Chi-Square Continuity Correctiona Likelihood Ratio Fisher's Exact Test Linear-by -Linear Association N of Valid Cases
Value 1,087b ,696 1,091
1,078
df 1 1 1
Asy mp. Sig. (2-sided) ,297 ,404 ,296
1
Exact Sig. (2-sided)
Exact Sig. (1-sided)
,404
,202
,299
120
a. Computed only f or a 2x2 table b. 0 cells (,0%) hav e expected count less than 5. The minimum expected count is 15,50.
Risk Estimate
Value Odds Ratio f or cara. persalinan (SC / Perv aginam) For cohort Kelompok = Kasus For cohort Kelompok = Kontrol N of Valid Cases
95% Conf idence Interv al Lower Upper
1,549
,678
3,539
1,230
,849
1,783
,794
,502
1,256
120
63
D. Gawat Janin Crosstab
Gawat janin
Ya
Tidak
Total
Kelompok Kasus Kontrol 21 3 12,0 12,0 35,0% 5,0% 17,5% 2,5% 39 57 48,0 48,0 65,0% 95,0% 32,5% 47,5% 60 60 60,0 60,0 100,0% 100,0% 50,0% 50,0%
Count Expected Count % wit hin Kelompok % of Total Count Expected Count % wit hin Kelompok % of Total Count Expected Count % wit hin Kelompok % of Total
Total 24 24,0 20,0% 20,0% 96 96,0 80,0% 80,0% 120 120,0 100,0% 100,0%
Chi-Square Tests
Pearson Chi-Square Continuity Correctiona Likelihood Ratio Fisher's Exact Test Linear-by -Linear Association N of Valid Cases
Value 16,875b 15,052 18,581
16,734
df 1 1 1
1
Asy mp. Sig. (2-sided) ,000 ,000 ,000
Exact Sig. (2-sided)
Exact Sig. (1-sided)
,000
,000
,000
120
a. Computed only f or a 2x2 table b. 0 cells (,0%) hav e expected count less than 5. The minimum expected count is 12,00.
Risk Esti mate
Value Odds Rat io f or Gawat janin (Y a / Tidak) For cohort Kelompok = Kasus For cohort Kelompok = Kont rol N of Valid Cases
95% Conf idence Interv al Lower Upper
10,231
2,855
36,666
2,154
1,619
2,865
,211
,072
,615
120
64
E. Riwayat resusitasi Crosstab
Resusitasi
Ya
Tidak
Total
Kelompok Kasus Kontrol 30 7 18,5 18,5 50,0% 11,7% 25,0% 5,8% 30 53 41,5 41,5 50,0% 88,3% 25,0% 44,2% 60 60 60,0 60,0 100,0% 100,0% 50,0% 50,0%
Count Expected Count % wit hin Kelompok % of Total Count Expected Count % wit hin Kelompok % of Total Count Expected Count % wit hin Kelompok % of Total
Total 37 37,0 30,8% 30,8% 83 83,0 69,2% 69,2% 120 120,0 100,0% 100,0%
Chi-Square Tests
Pearson Chi-Square Continuity Correctiona Likelihood Ratio Fisher's Exact Test Linear-by -Linear Association N of Valid Cases
Value 20,671b 18,912 21,857
20,499
df 1 1 1
1
Asy mp. Sig. (2-sided) ,000 ,000 ,000
Exact Sig. (2-sided)
Exact Sig. (1-sided)
,000
,000
,000
120
a. Computed only f or a 2x2 table b. 0 cells (,0%) hav e expected count less than 5. The minimum expected count is 18,50.
Risk Esti mate
Value Odds Rat io f or Resusitasi (Y a / Tidak) For cohort Kelompok = Kasus For cohort Kelompok = Kontrol N of Valid Cases
95% Conf idence Interv al Lower Upper
7,571
2,967
19,318
2,243
1,620
3,106
,296
,149
,589
120
65
F. Masa Gestasi Crosstab
Masa gestasi
preterm
Kelompok Kasus Kontrol 6 8 7,0 7,0 10,0% 13,3% 5,0% 6,7% 54 52 53,0 53,0 90,0% 86,7% 45,0% 43,3% 60 60 60,0 60,0 100,0% 100,0% 50,0% 50,0%
Count Expected Count % wit hin Kelompok % of Total Count Expected Count % wit hin Kelompok % of Total Count Expected Count % wit hin Kelompok % of Total
aterm
Total
Total 14 14,0 11,7% 11,7% 106 106,0 88,3% 88,3% 120 120,0 100,0% 100,0%
Chi-Square Tests Value ,323b ,081 ,324
Pearson Chi-Square Continuity Correctiona Likelihood Ratio Fisher's Exact Test Linear-by -Linear Association N of Valid Cases
,321
df 1 1 1
Asy mp. Sig. (2-sided) ,570 ,776 ,569
1
Exact Sig. (2-sided)
Exact Sig. (1-sided)
,777
,389
,571
120
a. Computed only f or a 2x2 table b. 0 cells (,0%) hav e expected count less than 5. The minimum expected count is 7,00.
Risk Esti mate
Value Odds Rat io f or Masa gestasi (preterm / aterm) For cohort Kelompok = Kasus For cohort Kelompok = Kontrol N of Valid Cases
95% Conf idence Interv al Lower Upper
,722
,234
2,224
,841
,447
1,584
1,165
,711
1,908
120
66
ANALISIS MULTIVARIAT REGRESI LOGISTIK Omnibus Tests of Model Coefficients St ep 1
St ep 2a
Chi-square 66.463 66.463 66.463 -.471 65.991 65.991
St ep Block Model St ep Block Model
df 5 5 5 1 4 4
Sig. .000 .000 .000 .492 .000 .000
a. A negat iv e Chi-squares v alue indicates that the Chi-squares v alue has decreased f rom the prev ious step.
Model Summary St ep 1 2
-2 Log Cox & Snell likelihood R Square a 99.893 .425 100.364a .423
Nagelkerke R Square .567 .564
a. Estimation terminat ed at iteration number 6 because parameter est imat es changed by less than .001.
Classificati on Tablea Predicted
St ep 1
Observ ed Kelompok
St ep 2
Ov erall Percentage Kelompok Ov erall Percentage
a. The cut v alue is . 500
Kasus Kontrol Kasus Kontrol
Kelompok Kasus Kontrol 43 17 7 53 43 6
17 54
Percent age Correct 71.7 88.3 80.0 71.7 90.0 80.8
67
Variables i n the Equation
Step a 1
Step a 2
Umur.ibu BBL sex Resusitasi gawat.janin Constant Umur.ibu BBL Resusitasi gawat.janin Constant
B -.095 .001 .478 4.173 2.367 -13.470 -.089 .001 4.091 2.343 -12.819
S.E. .044 .001 .709 1.082 .743 3.675 .043 .001 1.075 .737 3.541
Wald 4.599 3.458 .455 14.866 10.148 13.434 4.276 3.419 14.479 10.097 13.109
df 1 1 1 1 1 1 1 1 1 1 1
Sig. .032 .063 .500 .000 .001 .000 .039 .064 .000 .001 .000
Exp(B) .910 1.001 1.613 64.891 10.667 .000 .915 1.001 59.813 10.417 .000
95.0% C.I.f or EXP(B) Lower Upper .834 .992 1.000 1.002 .402 6.471 7.780 541.231 2.486 45.768 .841 1.000 7.271 2.455
.995 1.002 492.023 44.206
a. Variable(s) entered on st ep 1: Umur.ibu, BBL, sex, Resusitasi, gawat.janin.
Model if Term Removed
Variable St ep Umur.ibu 1 BBL sex Resusitasi gawat. janin St ep Umur.ibu 2 BBL Resusitasi gawat. janin
Model Log Likelihood -52.419 -51.835 -50.182 -67.728 -56.240 -52.469 -52.059 -67.904 -56.415
Change in -2 Log Likelihood 4.946 3.778 .471 35.563 12.588 4.575 3.754 35.445 12.466
df 1 1 1 1 1 1 1 1 1
Sig. of the Change .026 .052 .492 .000 .000 .032 .053 .000 .000
Variables not in the Equation St ep 2a
Variables Ov erall Statistics
Score .458 .458
sex
df 1 1
Sig. .498 .498
a. Variable(s) remov ed on step 2: sex.
95% CI Step
2
Variabel
p
OR Bawah
Atas
Infeksi IU
0,008
9,668
1,104
84,669
Gawat Janin
0,000
10,231
2,855
36,666
Resusitasi
0,000
7,384
0,284
19,167
Umur ibu
0,039
0,915
0,841
0,995
BBL
0,064
1,001
1,000
1,002
68
Lampiran 5. Dokumentasi
