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Klinische biologie Kernlabo Overzicht referentiewaarden Hematologie en Hemostase

KHB/L11 Versie: 7.0.0 Versiedatum: 20.05.2014

REFERENTIEWAARDEN AFDELING HEMATOLOGIE

Parameter

Matrix (S/B/U/LV)

Eenheid Leeftijd (j/m/d)

Geslacht Referentie(M/V) waarde

Sedimentatie

B

mm/u

0 – 17j 17 – 60j 60 – 70j 70 – 120j 0 – 50j 50 – 60j 60 – 70j 70 – 120j

V V V V M M M M

Hematocriet

B

%

0 – 8d 8 – 15d 15 – 61d 2 – 24m 2 – 6j 6 – 12j 12 – 19j 19 – 120j

Hemoglobine

B

g/dl

0 – 8d 8 – 15d 15 – 31d 31 – 183d 6 – 24m 2 – 6j 6 – 12j 12 – 19j 19 – 120j

Erytrocyten

B

12

.10 /l

0 – 15d 15 – 31d 31 – 92d 3 – 6m 6 – 24m 2 – 6j 6 – 12j 12 – 19j 19 – 120j

Auteur: Francine Vertessen Autorisator: Herman Goossens

Bron

0 – 10 0 – 19 0 – 20 0 – 35 0 – 10 0 – 12 0 – 14 0 – 30

Van toepassing sinds: 1995 1995 1995 1995 1995 1995 1995 1995

M V M V

42 – 64 39 – 63 35 – 55 30 – 42 33 – 42 35 – 45 37 – 49 36 – 46 40 – 50 37 – 46

1995 1995 1995 1995 1995 1995 1995 1995 1995 1995

2 2 2 2 2 2 1 1 1 1

M V M V

14 – 22 12.5 – 20 11 – 18 10 – 13.5 10.5 – 13.5 11 – 14 11.5 – 15.5 13 – 16 12 – 16 13 – 17 12 – 15

1995 1995 1995 1995 1995 1995 1995 1995 1995 1995 1995

2 2 2 2 2 2 2 1 1 1 1

M V M V

3.6 – 6.3 3.0 – 5.4 2.7 – 4.9 3.1 – 4.5 3.7 – 5.3 3.9 – 5.3 4.0 – 5.2 4.5 – 5.3 4.1 – 5.1 4.4 – 5.5 3.8 – 4.8

1995 1995 1995 1995 1995 1995 1995 1995 1995 1995 1995

2 2 2 2 2 2 2 1 1 1 1

Onbeheerde kopie geldig Verboden te kopiëren

1 1 1 1 1 1 1 1

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Parameter

Matrix Eenheid Leeftijd (S/B/U/LV) (j/m/d)


MCV

B

fl

0 – 8d 8 – 31d 31 – 92d 3 – 6m 6 – 24m 2 – 6j 6 – 12j 12 – 19j 19 – 120j

M/V

MCH

B

pg

0 – 8d 8 – 31d 31 – 92d 3 - 6m 6 – 24m 2 – 6j 6 – 120j

MCHC

B

g/dl

reticulocyten

B

% 9

;10 /l

Leukocyten

B


9

.10 /l

Bron

90 – 125 85 – 120 80 – 115 75 – 105 70 – 86 73 – 85 77 – 95 78 – 99 76 – 96

Van toepassing sinds: 1995 1995 1995 1995 1995 1995 1995 1995 1995

M/V

31 – 37 28 – 40 26 – 34 25 – 35 23 – 31 24 – 30 27 – 32

1995 1995 1995 1995 1995 1995 1995

2 2 2 2 2 2 1

M/V

30 – 35

1995

99

0 - 3d 3 - 7d 7d – 120j 0 – 3d 3 – 7d 7d – 120j

M/V

2.52 – 8.96 0.84 - 3.84 0.84 – 2.56 73 – 536 33 – 179 33 – 119

9/4/2012 9/4/2012 9/4/2012 9/4/2012 9/4/2012 9/4/2012

1, 14 1, 14 1, 14 1, 14 1, 14 1, 14

0-1d 1-2d 2-7d 7-14d 14-30d 1-6m 6-12m 1-2j 2-4j 4-6j 6-8j 8-10j 10-16j 16-21j >21j

M/V

9.0-30.0 9.4-34.0 5.0-21.0 5.0-20.0 5.0-19.5 6.0-17.5 6.0-17.5 6.0-17.0 5.5-18.5 5.0-14.5 4.5-13.5 4.5-13.5 4.5-13.0 4.5-11.0 4.3-10.0

2013 2013 2013 2013 2013 2013 2013 2013 2013 2013 2013 2013 2013 2013 2013

18 18 18 18 18 18 18 18 18 18 18 18 18 18 18


2 2 2 2 2 2 2 2 1

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Parameter




Van Bron toepassing sinds:

B B B B B B

% % % % % %

M/V M/V M/V M/V M/V M/V

40.0 – 75.0 20.0 – 45.0 2.0 – 10.0 1.0 – 6.0 0 – 1.0 0 – 4.0

1995 1995 1995 1995 1995 1995

1 1 1 1 1 9

B

.10 /l

Lymfocyten

B

.10 /l

Monocyten

B

.10 /l

Eosinofielen

B

.10 /l

Basofielen

B

.10 /l

Trombocyten

B

MPV

B

Leucocytenformule Segmentkernige Lymfocyten Monocyten Eosinofielen Basofielen Atypische lymfocyten + plasmacellen Segmentkernige


9

0 – 3d 3 – 5d 5 – 31d 1 – 6m 6 – 12m 1 – 8j 8 – 16j 16 – 120j

M/V

2.9 – 14.5 1.8 – 7.2 1.8 – 5.4 1.0 – 8.5 1.5 – 8.0 1.5 – 8.0 1.8 – 8.0 2.0 – 7.0

1995 1995 1995 1995 1995 1995 1995 1995

3,2 3,2 3,2 3,2 3,2 3,2 3,2 1

9

0 – 14d 14 – 31d 1 – 6m 6 – 12m 1 – 2j 2 – 4j 4 – 6j 6 – 8j 8 – 10j 10 – 16j 16 – 120j

M/V

2.0 – 17 2.5 – 16.5 4.0 – 13.5 4.0 – 10.5 3.0 – 9.5 2.0 – 8.0 1.5 – 7.0 1.5 – 6.8 1.2 – 6.5 1.2 – 5.2 1.0 – 3.0

1995 1995 1995 1995 1995 1995 1995 1995 1995 1995 1995

2,4 2,4 2,4 2,4 2,4 2,4 2,4 2,4 2,4 2,4 1

9

0 – 31d 1 – 24m 2 – 16j 16 – 120j

M/V

0.1 – 1.7 0.1 – 1.2 0.1 – 0.8 0.2 – 1.0

1995 1995 1995 2014

2,4 2,4 2,4 1

9

0 – 31d 1 – 12m 1 – 120j

M/V

0 – 0.8 0 – 0.7 0 – 0.5

1995 1995 1995

2,4 1 1

9

1-120j

M/V

0.02 – 0.1

07/2006

1

.10 /l

M/V

140 – 440

1995

5

fl

M/V

7.6 – 10.9

02/05/2012

15

9


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Parameter

Matrix Eenheid Leeftijd Geslacht Referentie-waarde (S/B/U/LV) (j/m/d) (M/V)

Reticulocyten

B

%

9

.10 /l

Hemoglobine A2

Hemoglobine F

Hemoglobine S

B

B

%

%

0 – 3d M/V 3 – 7d 7– 365d 1 – 120j

3–7 1–3 0.1 – 2.0

Van toepassing sinds: 1995 1995 1995

Bron

0.5 – 2.5

2014

1

0 – 3d M/V 3 – 7d 7– 365d 1 – 6j 6 – 120j

110 – 450 50 – 150 50 – 100

1995 1995 1995

6 6 6

30 – 100 50 - 100

2014 2014

1 1

0 – 61d M/V 2 – 5m 5 – 8m 8– 12m 1 – 120j

0.4 – 1.9 2.1 – 2.8 2.1 – 3.1 2.0 –3.3

1995 1995 1995 1995

7 7 7 7

2.0 – 3.5

1995

7

0 – 7d M/V 7 – 14d 14 – 31d 31 – 61d 61 – 91d 91 – 120d 3 - 4m 4 - 5m 5 – 6m 6 – 8m 8– 10m 10 – 12m 1 – 120j

60 – 80 66 – 81 46 –67

1995 1995 1995

1 1 1

29 – 61

1995

1

15 – 56

1995

1

9.4 – 29

1995

1

9.4 – 29 2.3 – 22 2.7 – 13 2.3 – 12 1.5 – 5.0

1995 1995 1995 1995 1995

1 1 1 1 1

1.3 – 3.5

1995

1

0.2 – 1.2

1995

1

M/V

0

1995

10

M/V

0–3 rokers tot 10

1995

1

6 6 6

B

%

Carboxyhemoglobine B

%

>19j

APTT

sec

0 – 31d M/V 1-7m 7-12m 1-6j

21 – 33 24 – 33 24 – 30

2013 2013 2013 2013

16 16 16

6-11j

25 – 32

2013

16

11-19j >19j

25 – 30 23 – 31

2013 2013

16 17

B



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Parameter



PT

B

M/V

%

PT

B

INR

Fibrinogeen

B

mg/dl

D-dimeren

Factor II

Factor V

B

B

B


µg/ml

%

%

0 – 31d

Van toepassing sinds:

Bron

1-7m

72 – 122

2013

16

7-12m

71 – 128

2013

16

1-6j

89 – 121

2013

16

6-11j 11-19j >19j 0 – 6d 6 – 92d 3 – 12m 1 – 120j 0 – 31d 1-7m

86 – 116 81 – 118 78 – 123 0.5 – 1.48 0.5 – 1.26 0.6 – 1.20 0.9 – 1.20

16 16 17 8 8 8 8

130 – 330

2013 2013 2013 1995 1995 1995 1995 2013 2013

7-12m

160 – 400

2013

16

1-6y

170 – 350

2013

16

6-11j

180 – 360

2013

16

11-19j >19j

180 – 330 170 – 420

2013 2013

16 17

<3.49 <10.9 <0.65 <0.52 <0.75 <0.48

2013 2013 2013 2013 2013 2013 2013

16 16 16 16 16 17

60-109 77-134 81-126 77-116 70-120 87-153

01/02/2014 01/02/2014 01/02/2014 01/02/2014 01/02/2014 01/02/2014

16 16 16 16 16 17

56-148 66-141 68-143 62-127 55-119 77-148

01/02/2014 01/02/2014 01/02/2014 01/02/2014 01/02/2014 01/02/2014

16 16 16 16 16 17

M/V

M/V

0 – 31d 1-7m 7-12m 1-6j 6-11j 11-19j >19j

M/V

0-1m 1-7m 7-12m 1-6j 6-11j 11-19j >19j

M/V

0-1m 1-7m 7-12m 1-6j 6-11j 11-19j >19j

M/V


16

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Parameter

Matrix Eenheid Leeftijd Geslacht Referentie(S/B/U/LV) (j/m/d) (M/V) waarde

Factor VII

B

Factor VIII coagulans

B

Von Willebrand antigen

%

%

%

Van toepassing sinds:

Bron

38-129 41-148 61-111 61-127 55-115 58-198

01/02/2014 01/02/2014 01/02/2014 01/02/2014 01/02/2014 01/02/2014

16 16 16 16 16 17

1-7m 7-12m

67-141 70-213

01/02/2014 01/02/2014

16 16

1-6j 6-11j 11-19j >19j 0-1m

83-170 75-163 80-166 66-180

01/02/2014 01/02/2014 01/02/2014 01/02/2014

16 16 16 17

01/02/2014

16

01/02/2014

16

01/02/2014

16

01/02/2014

16

01/02/2014

16

01/02/2014

17

01/02/2014

17

02/2006 02/2006

13 15

01/02/2014 01/02/2014 01/02/2014 01/02/2014 01/02/2014 01/02/2014

16 16 16 16 16 17

0-1m 1-7m 7-12m 1-6j 6-11j 11-19j >19j 0-1m

1-7m

7-12m

1-6j

6-11j

11-19j

>19j

Von Willebrand activiteit

B

%

>19j

Collagen Binding Fact VIIIc antigen

B B

%

>19j >19j

Factor IX

B

%

0-1m 1-7m 7-12m 1-6j 6-11j 11-19j >19j


M/V

M/V

M/V Blgr O Blgr A/B M/V Blgr O Blgr A/B M/V Blgr O Blgr A/B M/V Blgr O Blgr A/B M/V Blgr O Blgr A/B M/V Blgr O Blgr A/B M/V Blgr O Blgr A/B M/V M/V

63-223 61-192 76-243 60-158 59-141 67-163 60-140 50-158 71-140 60-142 46-141 63-153 60-159 63-165 56-160 56-162 54-149 72-167 50-187 44-141 63-200 60-150 aanwezig

M/V


44-78 46-114 63-97 60-108 72-116 86-162

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Parameter



Factor X

B

0-1m 1-7m 7-12m 1-6j 6-11j 11-19j >19j 0-1m 1-7m 7-12m 1-6j 6-11j 11-19j >19j 0-1m 1-7m 7-12m 1-6j 6-11j 11-19j >19j 0-1m 1-7m 7-12m 1-6j 6-11j 11-19j >19j 0 – 31d 1-7m 7-12m 1-6j 6-11j 11-19j >19j 0-1m 1-7m 7-12m 1-6j 6-11j 11-19j >19j >19j

M/V

>19j >19j 1-7m 7-12m 1-6j 6-11j 11-19j >19j

M V M/V

Factor XI

Factor XII

B

B

Factor XIII

Antitrombine

Proteine C activiteit

%

%

%

%

B

B

%

%

APC resistentie

B

%

Proteine S free

B

%

Trombinetijd

B

sec


Van Bron toepassing sinds:

55-120 67-146 75-124 69-118 66-117 77-189

01/02/2014 01/02/2014 01/02/2014 01/02/2014 01/02/2014 01/02/2014

16 16 16 16 16 17

57-105 64-129 74-134 78-131 78-122 73-155

01/02/2014 01/02/2014 01/02/2014 01/02/2014 01/02/2014 01/02/2014

16 16 16 16 16 17

28-116 31-126 36-122 37-123 43-122 57-210

01/02/2014 01/02/2014 01/02/2014 01/02/2014 01/02/2014 01/02/2014

16 16 16 16 16 17

63-152 42-128 71-139 76-133 64-133 62-183

01/02/2014 01/02/2014 01/02/2014 01/02/2014 01/02/2014 01/02/2014

16 16 16 16 16 17

81 – 126 90 - 132 93 - 128 92 - 122 90 - 119 79 - 120

2013 2013 2013 2013 2013 2013

16 16 16 16 16 17

43-102 59-103 71-125 75-120 70-131 78-158 2.36-3.06

01/02/2014 01/02/2014 01/02/2014 01/02/2014 01/02/2014 01/02/2014 01/02/2012

16 16 16 16 16 17 17

79-145 56-143 16.2-24.9 15.4-21.1 15.3-19.7 14.5-19.9 15.2-24.0 15.5-19.4

01/02/2014 01/02/2014 01/02/2014 01/02/2014 01/02/2014 01/02/2014 01/02/2014 01/02/2014

17 17 16 16 16 16 16 17

M/V

M/V

M/V

M/V

M/V

M/V


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Bronnen: 1. Practical Haematology, eleventh edition, 2012, Dacie J.V. and Lewis S.M. Hfst 2: Reference ranges and normal values. 2. Dallman, 1977 3. Monroe et al. 1979 4. Weinberg et al, 1985 5. Wintrobe’s Clinical Haematology 10the edition, Vol2, 1998 Normal Blood and Bone Marrow values in Human, S.L.Perkin 6. Forestier et al, 1986 7. Metaxotron-Marromati et al, 1982 8. Blood Coagulation and Haemostasis, a practical fourth edition guide, M.Adrew, M.Johnston 9. Bayer Diagnostics, Tarrytown-USA 10. Helena Biosciences, U.K. 11. Diagnostica Stago, Asnières-France 12. / 13. Kordia, Nederland 14. Forestier et al, 1986 Reference ranges and normal values 15. Vandenbossche et al 16. Appel IM, Grimminck B, Geerts J, Stigter R, Cnossen MH, Beishuizen A. Age dependency of coagulation parameters during childhood and puberty, Journal of Thrombobis and Heamostasis 2012, 10: 22542263, 17. Siemens Healthcare Diagnostics, Anderlecht + in house verification. th 18. Wintrobe’s Clinical Haematology 12 edition 99. Historisch, bron niet meer terug te vinden



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