24 oktober 2005
exercise
PENGARUH RANGSANG EXERCISE TERHADAP HOMEOSTASIS
exercise nani cahyani sudarsono – dep. i faal FKUI 2005
metabolisme otot
Nani Cahyani Sudarsono
gerakan otot
REVIEWER: DEWI IRAWATI & MINARMA SIAGIAN DEPARTEMEN I FAAL FKUI
SISTEM DALAM TUBUH YANG TERLIBAT DALAM HOMEOSTASIS D U Silverthorn, Human Physiology An Integrated Approach
Figure 6-21: Comparison of local and reflex control Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Reflex Control
exercise
exercise
z Stimulus z Sensory receptor z Afferent path z Integration center z Efferent path z Effector- target cell/tissue z Response (feedback loop) Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
nani cahyani sudarsono – dep. i faal FKUI 2005
nani cahyani sudarsono – dep. i faal FKUI 2005
Control Pathways
ATP
Figure 6-22: Steps of a reflex
pengaruh exercise terhadap homeostasis nani cahyani sudarsono - Departemen I FAAL FKUI 2005 1
METABOLISME OTOT PANAS
24 oktober 2005
exercise
exercise
nani cahyani sudarsono – dep. i faal FKUI 2005
Sistem Kardiorespirasi
nani cahyani sudarsono – dep. i faal FKUI 2005
METABOLISME OTOT
ATP
METABOLISME OTOT
ATP
Bagaimana pengaturannya?
Otot
Gambar: D U Silverthorn, Human Physiology An Integrated Approach
exercise PERUBAHAN NEURONEURO-HORMONAL ↓ insulin ↑ glukagon ↑ simpatis nani cahyani sudarsono – dep. i faal FKUI 2005
nani cahyani sudarsono – dep. i faal FKUI 2005
HOMEOSTASIS ENERGI
↑ambilan & penggunaan glukosa di OTOT
exercise
PENGATURAN PERNAPASAN nani cahyani sudarsono – dep. i faal FKUI 2005
nani cahyani sudarsono – dep. i faal FKUI 2005
PERUBAHAN NEURONEURO-HORMONAL ↓ insulin ↑ glukagon ↑ simpatis
↑ambilan & penggunaan glukosa di OTOT
pengaruh exercise terhadap homeostasis nani cahyani sudarsono - Departemen I FAAL FKUI 2005 2
24 oktober 2005
pengaturan pernapasan
nani cahyani sudarsono – dep. i faal FKUI 2005
nani cahyani sudarsono – dep. i faal FKUI 2005
pengaturan pernapasan
Mempertahankan PO2 & PCO2 yang adekuat
frekuensi & kedalaman napas
Gambar: http://www.biology.eku.edu/RITCHISO/301notes6.htm
PERUBAHAN VENTILASI hubungannya dengan PO2, PCO2 & pH Gambar: Marieb – A.D.A.M.S Interactive Physiology: Respiratory System
exercise - peningkatan frekuensi & kedalaman pernapasan PUSAT PERNAPASAN
SARAF
PENGATURAN KERJA SISTEM KARDIOVASKULER
METABOLISME OTOT ↑
HORMON SARAF GERAKAN OTOT
PENINGKATAN KERJA OTOT PERNAPASAN
NAPAS LEBIH CEPAT, LEBIH DALAM
umpan balik
nani cahyani sudarsono – dep. i faal FKUI 2005
nani cahyani sudarsono – dep. i faal FKUI 2005
O2 ↓ CO2 ↑
um ke dpan epa n
DARAH
O2 ↑ CO2 ↓
DARAH SARAF
“NIAT”
INFORMASI DISAMPAIKAN MELALUI
EXERCISE
GAMBAR: http://web.ukonline.co.uk/webwise/spinneret/humans/inhexh.htm
nani cahyani sudarsono – dep. i faal FKUI 2005
exercise
Modulation of Contraction
Mempertahankan perfusi jaringan yang adekuat
TEKANAN DARAH Figure 14-12: Modulation of cardiac contraction by catecholamines Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
pengaruh exercise terhadap homeostasis nani cahyani sudarsono - Departemen I FAAL FKUI 2005 3
24 oktober 2005
Cardiovascular Response to Exercise
Cardiovascular Response to Exercise
Figure 25-7: Distribution of cardiac output at rest and during exercise
Figure 25-7: Distribution of cardiac output at rest and during exercise
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
exercise
nani cahyani sudarsono – dep. i faal FKUI 2005
nani cahyani sudarsono – dep. i faal FKUI 2005
Apa dampak peningkatan aliran darah ke otot?
click here
ATP
METABOLISME OTOT PANAS
HOMEOSTASIS SUHU TUBUH
METABOLISME OTOT
BAGAIMANA pengaturannya?
nani cahyani sudarsono – dep. i faal FKUI 2005
nani cahyani sudarsono – dep. i faal FKUI 2005
exercise
PANAS
pengaruh exercise terhadap homeostasis nani cahyani sudarsono - Departemen I FAAL FKUI 2005 4
24 oktober 2005
exercise
nani cahyani sudarsono – dep. i faal FKUI 2005
METABOLISME OTOT PANAS
Rhoades & Pflanzer, Human Physiology
Gambar: Marieb E, Human Anatomy & Physiology
exercise
exercise
nani cahyani sudarsono – dep. i faal FKUI 2005
nani cahyani sudarsono – dep. i faal FKUI 2005
berkeringat
HAUS
BAGAIMANA mekanismenya? HAUS
↑ ADH release from Posterior Pituitary
Cardiovascular Stretch Receptors
↑ Plasma ADH
Osmoreseptor
nani cahyani sudarsono – dep. i faal FKUI 2005
Dehydration
↓ Extracellular fluid volume
↑ Collecting Duct Water Permeability ↑ Plasma Osmolality
Normal Fluid Volume
Response to dehydration
↑ Water intake
↓ Water Excretion
pengaruh exercise terhadap homeostasis nani cahyani sudarsono - Departemen I FAAL FKUI 2005 5
Thirst
↑ Water Reabsorption
Courtesy of Dewi Irawati – Dep of Physiology FMUI
PENGATURAN IMBANGAN CAIRAN & ELEKTROLIT
24 oktober 2005
imbangan asam basa
PENGATURAN IMBANGAN ASAM - BASA nani cahyani sudarsono – dep. i faal FKUI 2005
nani cahyani sudarsono – dep. i faal FKUI 2005
pH tubuh optimal: 7.4 (6.9 - 7.7)
produksi H+ ↑ pada exercise (pH↓) ventilasi ↑
cairan ekstrasel: ekstrasel: plasma & sel darah merah respons pernapasan
respons ginjal
END NOTE nani cahyani sudarsono – dep. i faal FKUI 2005
nani cahyani sudarsono – dep. i faal FKUI 2005
END NOTE Pada seorang yang melakukan exercise, dapatkan Saudara menjelaskan mekanisme kerja berbagai sistem yang terlibat dalam homeostasis tubuh?
Pada seorang yang melakukan exercise, dapatkan Saudara menjelaskan mekanisme kerja berbagai sistem yang terlibat dalam homeostasis tubuh?
exercise sebagai rangsang: rangsang:
exercise:
z Homeostasis z Homeostasis z Homeostasis z Homeostasis z Homeostasis
z Homeostasis z Homeostasis z Homeostasis z Homeostasis z Homeostasis
dampak terhadap homeostasis?
sistemsistem-organ yang terlibat? terlibat?
energi cairan suhu tubuh asam-basa elektrolit
nani cahyani sudarsono – dep. i faal FKUI 2005
nani cahyani sudarsono – dep. i faal FKUI 2005
ekskresi H+
sistem buffer
energi cairan suhu tubuh asam-basa elektrolit
pengaruh exercise terhadap homeostasis nani cahyani sudarsono - Departemen I FAAL FKUI 2005 6
24 oktober 2005
exercise:
sistem kontrol
z Homeostasis z Homeostasis z Homeostasis z Homeostasis z Homeostasis
energi cairan suhu tubuh asam-basa elektrolit
nani cahyani sudarsono – dep. i faal FKUI 2005
nani cahyani sudarsono – dep. i faal FKUI 2005
sistem kontrol yang berperan? berperan?
z Cepat? Lambat? z Saraf? Endokrin? z Komunikasi antar sel? z Mekanisme?
{Feedback (umpan balik) {Feedforward (umpan ke depan)
manfaat melakukan exercise
manfaat melakukan
Hippocrates (460-370 SM)
nani cahyani sudarsono – dep. i faal FKUI 2005
nani cahyani sudarsono – dep. i faal FKUI 2005
exercise
if we could give every individual the right amount of nourishment and exercise, not too little and not too much, we would have found the safest way to health
nani cahyani sudarsono – dep. i faal FKUI 2005
manfaat melakukan exercise
Move for health
Raga aktif untuk sehat
pengaruh exercise terhadap homeostasis nani cahyani sudarsono - Departemen I FAAL FKUI 2005 7
