UNIVERSITAS AIRLANGGA DIREKTORAT PENDIDIKAN Tim Pengembangan Jurnal Universitas Airlangga Kampus C Mulyorejo Surabaya
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UNIVERSITAS AIRLANGGA DIREKTORAT PENDIDIKAN Tim Pengembangan Jurnal Universitas Airlangga Kampus C Mulyorejo Surabaya
EDITORIAL BOARD Dewan Redaksi MAJALAH ILMU FAAL INDONESIA The Indonesian Journal of Physiology VOLUME 10 NOMOR 2, SEPTEMBER 2013 Majalah Ilmu Faal Indonesia memuat tulisan ilmiah yang terkait dengan bidang fisiologi . Terbit setiap 4 bulan, berdasarkan SK Ketua Umum Pengurus Pusat Ikatan Ahli Ilmu Faal Indonesia No. 001/SK/IAIFI/IX/2000, tanggal 14 September 2000 Susunan Dewan Redaksi Ketua Penyunting Purwo Sri Rejeki Sekretaris Sundari Indah Wiyasihati Bendahara Ratna Damayanti Iklan dan Langganan Yuliati Penyunting Pelaksana Lilik Herawati Raden Argarini Aqsa Sjuhada Irfiansyah Irwadi Penyunting Teknik Kuncoro Puguh Santoso Tata Usaha Muhammad Taufik Kurniadi Alamat : Departemen Faal Fakultas Kedokteran Universitas Airlangga Jl. Mayjen. Prof. Dr. Moestopo 47 Surabaya 60132 Telp: (031) 5023621 Fax: (031) 5023621 Email:
[email protected] Rekening : Ratna Damayanti, drh., M.Kes Bank NIAGA IBC Dharmahusada Surabaya No. 033-01-11506-13-2 MAJALAH ILMU FAAL INDONESIA diterbitkan oleh Ikatan Ahli Ilmu Faal Indonesia (IAIFI) Harga berlangganan : Rp. 50.000,00 per nomor MAJALAH ILMU FAAL INDONESIA The Indonesian Journal of Physiology VOLUME 10 NOMOR 2, SEPTEMBER 2013 Majalah Ilmu Faal Indonesia memuat tulisan ilmiah yang terkait dengan bidang fisiologi . Terbit setiap 4 bulan, berdasarkan SK Ketua Umum Pengurus Pusat Ikatan Ahli Ilmu Faal Indonesia No. 001/SK/IAIFI/IX/2000, tanggal 14 September 2000 Susunan Dewan Redaksi Ketua Penyunting Purwo Sri Rejeki Sekretaris Sundari Indah Wiyasihati Bendahara Ratna Damayanti Iklan dan Langganan Yuliati Penyunting Pelaksana Lilik Herawati Raden Argarini Aqsa Sjuhada Irfiansyah Irwadi Penyunting Teknik Kuncoro Puguh Santoso Tata Usaha Muhammad Taufik Kurniadi Alamat : Departemen Faal Fakultas Kedokteran Universitas Airlangga Jl. Mayjen. Prof. Dr. Moestopo 47 Surabaya 60132 Telp: (031) 5023621 Fax: (031) 5023621 Email:
[email protected] Rekening : Ratna Damayanti, drh., M.Kes Bank NIAGA IBC Dharmahusada Surabaya No. 033-01-11506-13-2 MAJALAH ILMU FAAL INDONESIA diterbitkan oleh Ikatan Ahli Ilmu Faal Indonesia (IAIFI) Harga berlangganan : Rp. 50.000,00 per nomor
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UNIVERSITAS AIRLANGGA DIREKTORAT PENDIDIKAN Tim Pengembangan Jurnal Universitas Airlangga Kampus C Mulyorejo Surabaya
Table of Contents No 1
Title
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PERANAN SITOSKELETON MENJAGA STABILITAS DAN ELASTISITAS MEMBRAN ERITROSIT PENGARUH PERUBAHAN LETAK TITIK BERAT DAN TITIK TUMPU TUBUH KERJA BUBUT POSISI BERDIRI ERGONOMIS TERHADAP KELELAHAN OTOT BIOMEKANIK STUDY OF SOME BIOCHEMICAL PARAMETERS IN YOUNG MAN AS EFFECTED BY RAMADAN FASTING PENGARUH CURCUMIN TERHADAP KEKUATAN KONTRAKSI JANTUNG TIKUS BETINA YANG DIPERLAKUKAN ISKEMIA – REPERFUSI DENGAN METODE LANGENDORFF PLASTICITY BIOLOGIS SEL IMUNOKOMPETEN PADA PEMBERIAN DEXAMETHASON
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PERAN LEPTIN DALAM MENINGKATKAN DENSITAS TULANG
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UNIVERSITAS AIRLANGGA DIREKTORAT PENDIDIKAN Tim Pengembangan Jurnal Universitas Airlangga Kampus C Mulyorejo Surabaya Vol. 5 - No. 2 / 2006-02 TOC : 0, and page : 0 - 0 PERAN LEPTIN DALAM MENINGKATKAN DENSITAS TULANG PERAN LEPTIN DALAM MENINGKATKAN DENSITAS TULANG Author : Anwar Maruf | Fakultas Kedokteran Hewan Abstract The objective of this study was to identify the role of to leptin increase bone density. A post test only design study involving 32 female Wistar strain rats of 4 month-old as samples. These experimental animals received the following treatments : (1) 8 rats received standard amount of feeding for 2 months, (2) 8 rats received feeding 10% less than the standard amount for 2 months, (3) 8 rats received feeding 10% more than the standard amount for 2 months, (4) 8 rats received feeding ad libitum for 2 months. At day 60, 1.5 cc of blood was taken intracardially for leptin level examination using Elisa, followed with bone density examination in the metaphysical part of femoral bone using Ultrasound DBM Sonic 1200. Results showed that rats receiving 10% less than standard feeding had significant (p < 0,05) leptin lower concentration from those of other treatments. Leptin level of rats receiving 10% less than standard feeding was the lowest as compared to other treatment, while the leptin levels of rats receiving standard feeding, 10% more than standard, and ad libitum were not significantly different (p > 0,05). On bone density, rats receiving 10% less than standard feeding had the lowest bone density, and the density increased consecutively in rats receiving standard, 10% more, and ad libitum feeding. This indicate that increased bone density corresponds with increasing leptin level in rats. The higher the leptin level, the greater the increase of bone density. Keyword : leptin, bone, density, , Daftar Pustaka : 1. CM Ashwell, (1999). Effect of growth hormone and pair-feeding on leptin mRNA expression in liver and adipose tissue. Domestic Animal Endocrinology 17. - : 2. JP McMurtry, (1999). Effect of growth hormone and pair-feeding on leptin mRNA expression in liver and adipose tissue. Domestic Animal Endocrinology 17. - : 3. XH Wang, (1999). Effect of growth hormone and pair-feeding on leptin mRNA expression in liver and adipose tissue. Domestic Animal Endocrinology 17. - : 4. CH Chesnut, (1991). Theoritical overview : Bone development , peak bone mass, bone loss and fracture. Am. J. Med 91. - : 5. WF James, (2003). How to grow bone to treat osteoporosis and mend fracture. Current Osteoporosis Reports 1. - : 6. RF Jeanrenaud, (1996). Obesity, leptin and the brain . New England Journal of Medicine. - : 7. J Bernard, (1996). Obesity, leptin and the brain . New England Journal of Medicine. - : 8. S Margetic, (2002). Leptin : a review of its peripheral actions and interactions. International Journal of Obesity 26. - : 9. C Gazzola, (2002). Leptin : a review of its peripheral actions and interactions. International Journal of Obesity 26. - : 10. GG Pegg, (2002). Leptin : a review of its peripheral actions and interactions. International Journal of Obesity 26. - : 11. Hill, (2002). Leptin : a review of its peripheral actions and interactions. International Journal of Obesity 26. - : 12. U Meler, (2004). Endocrine regulation of energy metabolism : review of pathobiochemical and clinical chemical aspects of leptin, ghrelin, adiponectin and resistin. Clinical Chemistry 50. - : 13. AM Gressner, (2004). Endocrine regulation of energy metabolism : review of
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UNIVERSITAS AIRLANGGA DIREKTORAT PENDIDIKAN Tim Pengembangan Jurnal Universitas Airlangga Kampus C Mulyorejo Surabaya pathobiochemical and clinical chemical aspects of leptin, ghrelin, adiponectin and resistin. Clinical Chemistry 50. - : 14. DJ Pritchard, (1996). Instructional course lectures. American Academy of Orthopaedic Surgeons 45. - : 15. MP Richards, (2000). Quantitative analysis of leptin mRNA using comparative riverse transcriptase PCR and capillary electrophoresis with laser-induced fluorescence detection. Electrophoresis 21. - : 16. CN Ashwell, (2000). Quantitative analysis of leptin mRNA using comparative riverse transcriptase PCR and capillary electrophoresis with laser-induced fluorescence detection. Electrophoresis 21. - : 17. JP McMurtry, (2000). Quantitative analysis of leptin mRNA using comparative riverse transcriptase PCR and capillary electrophoresis with laser-induced fluorescence detection. Electrophoresis 21. - : 18. Roeshadi D, (2000). Round Table Discusion: Disuse osteoporosis . RS Husada Utama. Surabaya : -
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