DAFTAR PUSTAKA
Aisyah, S.I. 2007. Induksi kalus embriogenik pada kultur in vitro Jagung (Zea mays L.) dalam rangka peningkatan keragaman genetik melalui variasi somaklonal. Jurnal Ilmu-ilmu Pertanian Indonesia. Edisi Khusus, No. 3 2007, Hal. 344-350 Alaoui-Sosse, B.P. Genet, F. Vinit-Dunad, T. Marei-Laure, D.Epron, and P.M.Badot. 2004. Effect of Copper on Growth In Cucumber Plants (Cucumis sativus) and Its Relationship with Carbohydrate Accumulation and Changes in Ion Contents. Plants Science 30:1-6 Ali, M. B., Eun-Joo, H., Kee-Yoeup, P. 2006. Copper-Induced Changes in The Growth, Oxidative Metabolism, and Saponin Production in Suspension Culture Roots of Panax ginseng in Bioreactors. Plant Cell Rep 25: 1122-1132 Andaryani, S. 2010. Kajian Penggunaan Berbagai Konsentrasi BAP dan 2,4D terhadap Induksi Kalus Jarak Pagar (Jatropha curcas L.) secara In vitro. Skripsi. Fakultas Pertanian Universitas Sebelas Maret: Surakarta. Anonimous. 2009. Unsur-Unsur Essensial pada Tanaman. http://www.agrinaonline.com.Diakses pada 02 Februari 2015 Aprianita, Esyanti, R.R dan Siregar, A.H. 2003. Pengaruh Pemberian Elisitor Jamur Phytium aphanidermatum Ariati, S.N. 2012. Induksi Kalus Tanaman Kakao (Theobroma cacao L.) Pada Media MS dengan penambahan 2,4 D, BAP, dan air kelapa. Jurnal Natural Science 1 (1):78-84 Aringsih, I, Solichatun, dan Endang, A. 2003. Pertumbuhan Kalus dan Produksi Antrakuinon Mengkudu (Morinda citrifolia L.) pada Media Murashige –Skoog (MS) dengan penambahan Ion Ca2+ dan Cu2+. Jurnal Biofarmmasi Vol 1 (2):39-43. UNS: Surakarta Aryanti, T.M., Ermayanti, Kartika, I.P, Rita, M.D. 2006. Uji Daya Artemisia spp On Plasmodium falciparum, Majalah Farmasi Indonesia 17 (2) (2006). Badan POM RI. 2008. Taksonomi Koleksi Tanaman Obat Artemisia vulgaris L. Direktorat Obat Asli Indonesia. Jakarta Bhakuni, R.S., Jain, D.C., Sharma, R.P., and Kumar, S., 2001, Secondary metabolites of Artemisia annua and their biological activity, Current Science, 80 (1), 35-48. Bidweel, R.G.S. 1974. Plant Physiology. Macmilan Biology Series: New York
38
Bulan, S. A. 2008. Pengaruh Penambahan Ion Cu2+ dan Metil Jasmonat pada Produksi Asiatikosida Kultur Suspensi Sel Pegagan (Centella asiatica (L.) Urban). Skripsi Sarjana Farmasi Institut Teknologi Bandung Buletin Jendela Data dan Informasi Kesehatan. 2011. Epidemiologi Malaria di Indonesia. Kementerian Kesehatan RI. Jakarta CCRC Farmasi UGM. 2014. http://ccrc.farmasi.ugm.ac.id/?page_id=201. Diakses pada 8 November 2014 Changhiz A, Alireza M, Ali R, Mehrdad P, Behbood J. Antibacterial Activity of Methanolic Extract and essence of Sagebrush (Artemisia vulgaris) against Pathogenic Bacteria. Bull. Env. Pharmacol. Life Sci. 3 (2) 2014:121-125 Contin, A., R. Van de Heijden and R. Verpoorte. 1999. Effects of Alkaloid Precursor Feeding and Elicitation on The Accumulation of Secologanin in Catharanthus roseus Dell. Suspension Culture. Plant Cell Tissue and Org. Cult. 59. 111-119 Devlin, R.M. and Withan, F.H. 1983. Plant Physiology Fourth Edition. PWS Publisher: USA Doods, J.H and L.W. Roberts. 1985. Experiments Cambridge University Press: Cambridge
in Plant Tissue Culture.
Dwi, N.M. 2012. Pengaruh Pemberian Air Kelapa dan Berbagai Konsentrasi Hormon 2,4D pada Medium MS dalam Menginduksi Kalus Tanaman Anggur (Vitis vinera L.). Jurnal Natural Science 1(1): 53-62 Ebadi, N. 2007. Pharmacodynamic Basic of Herbal Medicine. CRC Press. London New York-Washington D.C. 726 p. Eilert, U., F. Constable, and W.G.W. Kurz, 1986. Elicitor stimulation of monoterpene indole alkaloid formation in suspension cultures of Catharanthus roseus. J. Plant Phys., 126, 11-22. Evans, D.E., J.O.D., Coleman, and A. Kearns. 2003. Plant Cell Culture. BIOS Scientific Publisher : New York Fatmawati, T.A., T. Nurhidayati, dan N. Jadid. 2008. Pengaruh Kombinasi Zat Pengatur Tumbuh IAA dan BAP pada kultur Jaringan Tembakau Nicotiana tabacum L. Var. Prancak 95. Institut Teknologi Sepuluh November: Surabaya Ferreira, J. and Janick, J., 2009, Annual Wormwood (Artemisia annua L.), www.hort.purdue.edu/newcrop/cropfactsheets/artemisia.pdf, diakses tanggal 18 Februari 2016 Ferreira, J.F.S., 2004, Artemisia annua L. : The hope against malaria and cancer, Medicinal and aromatic plants : Production, business and applications,
39
Proceedings of the January 15-17 meeting, Mountain State University, Beckley. _________, and Janick J. 1996. Immunoquantitative analysis of artemisinin from Artemisia annua using polyclonal antibodies. Phytochemistry 41: 97–104. Ferreira, J.F.S., J.C. Laughlin, N. Delabays and P.M. de Magalhaes. 2005. Cultivation and genetics of Artemisia annua L. for increase production of the antimalarial artemisinin. Plant Genetic Resources. III (2) : 206-229. Ferreira, J.F.S., Simon J.E. and J. Janick. 1995. Developmental studies of Artemisia annua: flowering and artemisinin production under greenhouse and field conditions. Planta Medica 61: 167–170. Firiani, A., Siregar, A.H., dan esyanti, R.R. 1999. Pengaruh Pemberian Homogenat Phytium aphanidermantum (Edson) Fitzp terhadap kandungan Ajmalisin dalam Kultur Kalus Tapak dara. Hayati 6 (3): 65-69 George, E. F. and P. H. Sherrington, 1984. Plant Propagation by Tissue Culture. Eastern Press Exegetic Ltd. England Haq, N. 2003. Production of Bioactive Coumpound. In vitro Production of Bioactive Compound from Medical and Raomatic Plant. ICUC. University of Southampton. U.K. 1-22 Harijanto P.N., 2006. Buku Ajar Ilmu Penyakit Dalam. Jakarta: PIP FKUI: 17321744. Hendaryono, D. dan A. Wijayani. 1994. Teknik Kultur Jaringan. Penerbit Kanisius: Yogyakarta Holm, L., Doll, J., Holm, E., Pancho, J. and Herberger, J. 1997. World weeds: Natural histories and distribution. John Wiley and Sons, New York, NY. 1129 pp. Hudayono, S. 2004. Pengaruh Berbagai Kondisi Oksidasi Terhadap Kandungan Kolesterol Dan Sterol Lain Dalam Lemak Coklat. Jurnal Sains 8 (2) :74-75 Kardinan, A. 2006. Tanaman Artemisia Penakluk Penyakit Malaria. http://www.kompas.com/kompas-cetak/0604/20/ilpeng/2592372.htm.Diakses tanggal 19 November 2014. Kovacs, M. 1992. Biological Indicator in Environmental Protection. Bedapest House of Hungarian Academy of Science. Krishna, S., Bustamante, L., Haynes, R.K., and Staines, H.M., 2008, Artemisinins: their growing importance in medicine, Trends in Pharmacological Sciences, 29 (10), 520-527.
40
Kristina, N. N., Rita, N., Siti, F.S. dan Molide, R. 2007. Peluang Peningkatan Kadar Kurkumin pada Tanaman Kunyit dan Temulawak. Balai Penelitian Tanaman Obat dan Aromatik. Lin, X., Yin, Z., Jianjun, Z., Xu, L., Fangyuan, Z., Qian, S., Shaoyan, W., Yunfei, C., Tao, W. and Kexuan, T. 2011. Enhancement of Artemisinin in Tetraploid Artemisia annua Plants by Modulating The Expression of Genesin Artemisinin Biosyntethic Pahtway. International Union of Biochemistry and Molecular Biology. Inc. 58:50-57 Logemann, E., Wu, S., Schroder, J., Schmelzer, E., Sommissich, I.E., Hahlbrock, K. 1995. Gene Activation by Uv Light, Fungal Elicitor or Fungal Infection in Petroselinum crispum in Correlated with Repression of Cell Cycle-Related Genes. The Plant Journal, 8 (6): 865-867 Lulu, Y., Chang, Z., Ying, H., Ruiyi, Y., and Qingping, Z., 2008, Abiotic stressinduced expression of artemisinin biosynthesis genes in Artemisia annua L., Chinese Journal of Applied & Environmental Biology, 14 (1), 001- 005. Mannan, A., Ibrar, A., Waheed, A., Muhammad, F. A., Rizwana, A.Q., Izhar, H., and Bushra, M. 2010. Survey of artemisinin production by diverse Artemisia species in northern Pakistan. Malaria Journal 2010, 9:310 Mantell, S.H., and Smith, H. 1983. Cultural Factor That Influence Secondary Metabolite Accumulation in Plant Cell and Tissue Cultures, dari Mantell , S.H, Smith, H. (eds.) Plant Biotechnology. Cambridge University Press : New York, 75-108 Marschner, H. 1995. Mineral Nutrition of Higher Plants. Vol. II . Academic Press : London, 337-347 Mukarlina, Esyanti, dan Siregar. 2006. Pengaruh Pemberian Elisitor Homogenat Jamur Pythium aphanidermatum (Edson) FITZP. terhadap Kandungan Ajmilisin dalam Kultur Akar Catharantus roseus (L) G. Don. Jurnal Matematika dan Sains, Vol. 11. No 2. Murashige, T. And F. Skoog. 1962. A Resived Medium for Rapid Growth and Bioassays with Tobacco Tissue Culture. Physiol Plant (15): 473-497 Muryanti, S. dan Endang, A. 2005. Pertumbuhan Dan Produksi reserpin Kalus Pule Pandak (Rauvolfia serpentine (L)) Bentham ex. Kurz) pada pemberian Metil Jasmonat Beroperasi in vitro. Jurnal Bioteknologi 2 (2): 58-66 Noggle, G. R. dan G. J. Fritz. 1983. Introductory Plant Physiology: Second Edition. Prentince-Hall, Inc. New Jersey. Nurachman Z., 2005. Artemisin, Pembunuh Parasit http:lunisosdem.oru/klipingdetail.php?aid2652&caid=I&=56
Malaria
.
41
Nurcahyani, N., Solichatun, dan Endang, A. 2008. The Reserpine Production and Callus Growth of Indian Snake Root (Rauvolfia serpentina (L.) Benth. Ex Kurz) Culture by Addition of Cu2+. Biodiversitas Vol. 9 (3) : 177-179 Oktafiana, L. 2010. Kultur Kalus Pegagan (Centella asiatica (L.) Urban). dengan Penambahan Ion Cu2+ sebagai Elisitor dan Uji Kualitatif Kandungan Campuran Triterpenoid. Skripsi Sarjana Biologi Universitas Andalas Paniego and Giulieth .1994. Artemisia annua L.: Dedifferentiated and Differentiated Cultures. Plant Cell. Tissue Culture and Organ Culture 36: 163-168 Pierik, R.L.M. 1987. In Vitro Culture of Higher Plants. Netherland: Martinus Nijhoff Publisher Prawiranata, W., S. Harran dan P. Tjondronegoro.1995. Dasar-Dasar Fisiologi Tumbuhan Jilid 1. Departemen Botani FMIPA IPB : Bogor Rahayu, R., Solichatun dan Endang, A. 2003. Pengaruh Asam 2,4 Diklorofenoksiasetat (2,4 D) terhadap Pembentukan dan Pertumbuhan Kalus serta Kandungan Flavonoid Kultur Kalus Acalyptha indica L. Biofarmasi 1 (1): 1-6 UNS : Surakarta Rohman, A. 2009. Kromatografi untuk Analisis Obat Edisi Pertama. Graha Ilmu: Yogyakarta Rosmarkam, A. dan Nasih, W.Y. 2002. Ilmu Kesuburan Tanah. Penerbit Kansius: Yogyakarta Salisbury, F.B. dan C.W. Ross. 1995. Fisiologi Tumbuhan Jilid 3. Penerjemah: Lukman, D.R. dan Sumaryono. Bandung: Penerbit ITB Salisbury, F.B. dan C.W. Ross. 1996. Fisiologi Tumbuhan. Penerjemah: Lukman, D.R. dan Sumaryono. Bandung: Penerbit ITB Santoni, A. 1995. Seskuiterpenlakton dan Steroid dari Daun Sudamala (Artemisia vulgaris L.). Lembaga Penelitian Universitas Andalas. Santoso, U. dan F. Nursandi. 2002. Kultur jaringan tanaman. Malang : UMM Pers. Savitri, E. S., dan Nawafila, F. 2013. The Effect of Metal Ion Cu2+ for Development and Secondary Metabolites (Stig-masterol and Sitosterol) Callus of Purwoceng (Pimpinella alpine Molk.). Proceeding International Conference, 2013, The 4th Green Technology Faculty of Science and Technology Islamic of University State Maulana Malik Ibrahim Malang Sharaf-Eldin, M. and Elkholy, S., 2009, Artemisinin production from shoot culture systems of Artemisia annua L., Australian Journal of Basic and Applied Sciences, 3 (3), 2212-2216.
42
Siregar, L.A.M, Keng, C.L, dan Lim, B.P. 2006.Pertumbuhan dan Akumulasi Alkaloid dalam Kalus dan Suspensi Sel Eurycoma longifolia Jack. Jurnal Ilmiah Pertanian KULTURA. 1 (1) Soetjipto, H. dan Elizabeth, B.E.K. 2013. Komposisi Minyak Atsiri Tanaman Baru Cina (Artemisia vulgaris) yang Diperoleh Melalui Cara Penyulingan Uap dan Air. Prosiding Seminar Nasional Sains dan Pendidikan Sains VIII, Fakultas Sains dan Matematika, UKSW. Vol 4, No.1 Suryowinoto, M. 2000. Pemuliaan Tanaman Secara In Vitro. Pusat Antar Universitas Bioteknologi. UGM : Yogyakarta Sutini, B., Tatik, W., Wahyu, W., Sutiman, B.S. 2008. Meningkatkan Produksi Flavan-3-ol Melalui Kalus Camelia sinensis L. Dengan Elisitor Cu2+. Jurnal Berk.Panel.Hayati (14) : 39-44 Sutter, E.G. 1996. General Laboratory Requirements, Media and Sterilization Methods. CRC Press: Florida, USA Tisdale, S.L., W.L. Nelson, and J.D. Beaton. 1994. Soil Fertility and Fertilizer. New York : Macmilan Publishing Company Tjitra E., 2004. Pengobatan malaria dengan kombinasi artemisin. Dipresentasikan dalam symposium nasional pengendalian malaria pada tanggal 29-30 November 2004 di Surabaya Tjitra, E. 1994. Obat-Obat Baru Antimalaria. Cermin Dunia Kedokteran. Towler and Weathers 2007; Schramek et al. 2007 cit Mannan, A., Ibrar, A., Waheed, A., Muhammad, F. A., Rizwana, A.Q., Izhar, H., and Bushra, M. 2010. Survey of artemisinin production by diverse Artemisia species in northern Pakistan. Malaria Journal 2010, 9:310 Triani, L. 2006. Desorpsi Ion Logam Tembaga (II) dari Biomassa Chlorella Sp. Yang Termobilisasi dalam Silica Gel. Jurusan Kimia Universitas Negeri Semarang : Semarang USDA NRCS National Plant Database .2014. http://plants.usda. gov/ core/ profile? symbol=arvu. Diakses pada 8 November 2014 Utut, W. 2011. Keragaman Genetik Artemisia annua L. dan Artemisia vulgaris L. Berdasarkan Amplified Fragment Length Polymorphism (AFLP) dan Sifat Morfologi. http://repository.ipb.ac.id/handle/123456789/52552. Diakses pada 20 Januari 2015 Vasconsuelo, A. and Boland, R. 2007. Molecular aspects of the early stages of elicitation of secondary metabolites in plants. Plant Science 172: 861–875.
43
Wang, J. And V.P. Evangelou. 1995. Metal Tolerance Aspect of Plant Cell Wall and Vacuola in Pessarakti, M. (Ed).Handbook of Plant and Crop Stress. New York. Marcel Dekker. Inc Wang, S.H., Z., M. Yang, H. Yang, B.Lu, S., Q. Li and Y.P. Lu. 2004. CopperInduced Stress and Antioksidative Response in Roots of Brassica juncea L. Botanical Bulletin of Academia Sinica 45: 203-212 Wetherell, D. F., 1987. Pengantar Propagasi Tanaman secara In Vitro. Terjemahan : Koensumardiyah. Avery Publishing Group Inc., Wayne, New Jersey. WHO. 2010. Guidlines for The Treatment of Malaria. http://www.indonesianpublichealth.com/2014/07/pengobatan-malaria.html. Diakses pada 22 November 2014 Widoretno, S. 2003. Pengaruh Penambahan Nitrat dan Cu terhadap Konsentrasi Cu dalam Organ Arachis hypogeal L. BioSMART Vol 5., No. 2. Hal 94-97 Winoto, E., Dyah, I., Irmanida, B., dan Upik, K. H. 2013. Formulasi Larvasida Nabati Berbasis Minyak Biji Kamandrah (Croton tiglium L.) Terstandar sebagai Pencegah Penyakit Demam Berdarah Dengue. Bul. Littro, Volume 24, Nomor 2, Desember 2013. Yuzerman, B. 1996. Pengaruh 2,4 D dan Kinetin terhadap Pertumbuhan dan Kandungan Alkaloida Kalus Kecubung (Datura metel L.) yang Diberi Cahaya Ultra Violet pada Medium Murashige dan Skoog. Skripsi Sarjana Biologi FMIPA Universitas Andalas. Padang Zainab. 2007. Pengaruh Ion Tembaga dan Kobalt terhadap kandungan Kumarin dan Profil Kromatogram Lapis Tipis Metabolit Sekunder Kultur Sel Pacar Air (Impatiens balsamina L.). Universitas Gadjah Mada. Yogyakarta Zeng, Q., Zeng, X., Yin, L., Yang, R., Feng, L., and Yang, X., 2009, Quantification of three key enzymes involved in artemisinin biogenesis in Artemisia annua by polyclonal antisera-based ELISA, Plant Molecular Biology Reporter, 27, 5057. Zhao J, W. Zhu, Q. Hu. 2001. Enhanced Catharantine Production In Catharanthus roseus Cell Cultures By Combined Elicitor Treatmen In Shake Flask and Bioreactors. Enzym Microb Technol. 28 (7-8):673-681 Zhao, L.H., Ba, X.Q., Wang, X.G., Zhu, X.J., Wang, L. and Zeng, L. 2005. BAF complex is closely Related to And Interacts with NF1/CTF and RNA Polymerase II in Gene Transciptional Actiation. Acta. Biochim. Biophys.Sin (Shanghai), 37:440-6 Zulkarnain. 2009. Kultur Jaringan Tanaman. Jakarta: Bumi Aksara.