ACTA MEDICINAE 2/2013 Kompletní literatura ALERGOLOGIE, PNEUMOLOGIE 2
Alergologie a klinická imunologie v roce 2013
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Patogeneze chronické obstrukční plicní nemoci a možnosti protizánětlivé léčby
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Atopický ekzém – co nového v léčbě?
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Kontaktní ekzém – kontaktní alergeny
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Léčba atopické dermatitidy v přehledu
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Role vitaminu D u chronických zánětlivých onemocnění
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Doporučené postupy v léčbě astmatu bronchiale
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Rinosinusitidy: od praktického lékaře do specializované péče ORL nebo alergologie?
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Využití salinických roztoků v léčbě onemocnění horních cest dýchacích
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Kardiovaskulární bezpečnost indakaterolu v léčbě chronické obstrukční plicní nemoci
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Novinky v léčbě karcinomu plic
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Chronická obstrukční plicní nemoc
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Flutikazon furoát v léčbě alergické rýmy
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Léčba pacienta IFN-β-1b (Betaferonem)
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Využití certolizumab pegolu v léčbě aktivní revmatoidní artritidy
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Účinná léčba abataceptem v první linii u pacientky s diabetem mellitem I. typu a s revmatoidní artritidou
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Subkutánní interferon beta-1a v léčbě roztroušené sklerózy
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Systémová léčba osteolýzy indukované nádorem
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Antitrombotická léčba – léčba apixabanem
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Novinky ve fekální bakterioterapii
prof. MUDr. Václav Špičák, CSc. Immuno-flow, s. r. o., Praha, Česká iniciativa pro astma, o. p. s. MUDr. Jan Chlumský, Ph.D. Pneumologická klinika 1. LF UK, Thomayerova nemocnice, Praha
Prim. MUDr. Štěpánka Čapková Dermatologické oddělení pro děti, FN Motol, Praha RNDr. Dana Nováková Klinika nukleární medicíny a endokrinologie UK 2. LF a FN Motol, Praha doc. MUDr. Eliška Dastychová, CSc. I. dermatovenerologická klinika LF MU a FN u sv. Anny v Brně MUDr. Radek Litvik Kožní oddělení FN Ostrava
MUDr. Jana Čepová, Ph.D., MBA | MUDr. Margareta Beyerová | Ing. Eva Klapková, Ph.D. | Ing. Marta Pechová | prof. MUDr. Richard Průša, CSc. Ústav lékařské chemie a klinické biochemie, 2. LF UK a FN v Motole, Praha MUDr. Václava Bártů, Ph.D. Plicní oddělení, Medicon, a. s., Praha MUDr. Jan Pokorný, CSc. DG Centrum Ostrava, ORL
MUDr. Jiří Slíva, Ph.D. Ústavy farmakologie 2. a 3. LF UK, Praha
Prim. MUDr. Norbert Pauk, Ph.D. Klinika pneumologie Nemocnice Na Bulovce a 3. LF UK Praha
prof. MUDr. Jana Skřičková, CSc. | MUDr. Marcela Tomíšková | MUDr. Bohdan Kadlec | MUDr. Lenka Jakubíková, Ph.D. | MUDr. Jana Špaldová Klinika nemocí plicních a tuberkulózy LF MU a FN Brno doc. RNDr. Ladislav Dušek, Ph.D. Institut biostatistiky a analýz LF a PF MU Brno MUDr. Lucie Cwiková Městská nemocnice Ostrava-Fifejdy MUDr. Ester Seberová RESPIRAL, s. r. o., Plzeň
MUDr. Magdaléna Hladíková, Ph.D. Neurologická klinika LF MU a FN Brno MUDr. David Suchý, PhD. Oddělení klinické farmakologie FN Plzeň
MUDr. Petr Kopsa Revmatologické a rehabilitační oddělení Thomayerovy nemocnice, Praha
MUDr. Iva Okáčová | doc. MUDr. Pavel Štourač, Ph.D. Neurologická klinika LF MU a FN Brno, CEITEC – Středoevropský technologický institut MU Brno MUDr. Simona Paulíková | prof. MUDr. Jiří Petera Ph.D. | MUDr. Adam Paulík LF UK a Klinika onkologie a radioterapie FN Hradec Králové MUDr. Hynek Poul Oddělení hematologie a transfuziologie Nemocnice Pelhřimov, p. o. prof. Ing. Jaroslav Petr, DrSc. Výzkumný ústav živočišné výroby, Praha
Alergologie a klinická imunologie v roce 2013 prof. MUDr. Václav Špičák, CSc. Immuno-flow, s. r. o., Praha, Česká iniciativa pro astma, o. p. s. 1 Blahoš, J. – Ticháček, B.: STOROČENKA, historie České lékařské společnosti J. E. Purkyně, ČLS JEP, 2005. 2 Špičák, V.: Genetika alergie. In: Petrů, V.: Dětská alergologie, Mladá fronta, 2012, s. 35. 3 Špičák, V.: Etiopatogeneze alergie. In: Petrů, V.: Dětská alergologie, Mladá fronta, 2012, s. 66. 4 Bochner, B. B., et al.: Advances in mechanisms of allergy and clinical imunology in 2012. J Allergy Clin Immunol, 2013, v tisku. 5 Kauffmann, F. – Demenais, F.: Gene-environment interactions in asthma and allergic diseases: Challenges and perspectives. JACI, 2012, 130, s. 1229–1240. 6 Yang, I. V. – Schwarz, D. A.: Epigenetic mechanisms and the
development of asthma. JACI, 2012, 130, s. 1243–1255. 7 Choy, D. F., et al.: Gene expression patterns of Th2 inflammation and intercellular communication in asthmatic airways. The Journal of Immunology, 2011, 186, s. 1861–1869. 8 Woodruff, P. C., et al.: T-helper type 2-driven inflammation defines major subphenotypes of asthma. American J of Respiratory and Critical Care Medicine, 2009, 180, s. 388–395. 9 Von Gunten, S., et al.: Update in clinical allergy and immunology. Allergy, 2012, 67, s. 1491–1500. 10 Soyer, O. U., et al.: Mechanisms of peripheral tolerance to allergens. Allergy, 2013, 68, s. 161–170. 11 Špičák, V.: České stopy v alergologii. Alergie, 2012, 14, s. 246–250.
Patogeneze chronické obstrukční plicní nemoci a možnosti protizánětlivé léčby MUDr. Jan Chlumský, Ph.D. Pneumologická klinika 1. LF UK, Thomayerova nemocnice, Praha 1 Bateman, E. D. – Rabe, K. F. – Calverley, P. M. A. – Goehring, U. M. – Brose, M. – Bredenbroker, D., et al.: Roflumilast with long-acting + 2-agonists for COPD: influence of exacerbation history. European Respiratory Journal, 2011, 38, s. 553–560. 2 Bourdin, A. – Burgel, P.-R. – Chanez, P. – Garcia, G. – Perez, T. – Roche, N.: Recent advances in COPD: pathophysiology, respiratory physiology and clinical aspects, including comorbidities. European Respiratory Review, 2009, 18, s. 198–212. 3 Burgel, P.-R. – Bourdin, A. – Chanez, P. – Chabot, F. – Chaouat, A. – Chinet, T., et al.: Update on the roles of distal airways in COPD. European Respiratory Review, 2011, 20, s. 7–22. 4 Calverley, P. – Rabe, K. – Goehring, U. – Kristiansen, S. – Fabbri, L. – Martinez, F., et al.: Roflumilast in symptomatic chronic obstructive pulmonary disease: two randomised clinical trials. Lancet, 2009, 374, s. 685–694. 5 Celli, B. R. – MacNee, W. – Agusti, A. – Anzueto, A. – Berg, B. – Buist, A. S., et al.: Standards for the diagnosis and treatment of patients with COPD: A summary of the ATS/ERS position paper. Eur Respir J, 2004, 23, s. 932–946. 6 Fabbri, L. – Calverley, P. – Izquierdo-Alonso, J. – Bundschuh, D. – Brose, M. – Martinez, F., et al.: Roflumilast in moderate-to-severe chronic obstructive pulmonary disease treated with longacting bronchodilators: two randomised clinical trials. Lancet, 2009, 374, s. 695–703. 7 Gibson, G.: Pulmonary hyperinflation a clinical overview. Eur Respir J, 1996, 9, s. 2640–2649. 8 Gibson, G.: Lung volumes and elasticity. Clin Chest Med, 2001, 22, s. 623–635. 9 Grootendorst, D. C. – Gauw, S. A. – Verhoosel, R. M. – Sterk, P. J. – Hospers, J. J. – Bredenbroker, D., et al.: Reduction in sputum
neutrophil and eosinophil numbers by the PDE4 inhibitor roflumilast in patients with COPD. Torax, 2007, 62, s. 1081–1087. 10 Hatzelmann, A. – Morcillo, E. – Lungarella, G. – Adnot, S. – Sanjar, S. – Beume, R., et al.: The preclinical pharmacology of roflumilast—a selective, oral phosphodiesterase 4 inhibitor in development for chronic obstructive pulmonary disease. Pulm Pharmacol Ther, 2010, 23, s. 235–256. 11 McIvor, R. A.: Future options for disease intervention: Important advances in phosphodiesterase 4 inhibitors. European Respiratory Review, 2007, 16, s. 105–112. 12 O‘Donnell, D. – Laveneziana, P.: Physiology and consequences of lung hyperinflation in COPD. Eur Respir Rev, 2006, 15, s. 61–67. 13 O‘Donnell, D. – Laveneziana, P.: The clinical importance of dynamic lung hyperinflation in COPD. COPD, 2006, 3, s. 219–232. 14 O‘Donnell, D. – Webb, K.: Exertional breathlessness in patients with chronic airflow limitation. The role of lung hyperinflation. Am Rev Respir Dis, 1993, 148, s. 1351–1357. 15 O´Donnell, D. E. – Bredenbroker, D. – Brose, M. – Webb, K. A.: Physio logical effects of roflumilast at rest and during exercise in COPD. European Respiratory Journal, 2012, 39, s. 1104–1112. 16 Rabe, K.: Roflumilast for the treatment of chronic obstructive pulmonary disease. Expert Rev Resp Med, 2010, 4, s. 543–555. 17 Rabe, K. – Hurd, S. – Anzueto, A. – Barnes, P. – Buist, S. – Calverley, P., et al.: Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med, 2007, 176, s. 532–555. 18 Suissa, S. – Barnes, P.: Inhaled corticosteroids in COPD: the case against. Eur Respir J, 2009, 34, s. 13–16. 19 White, W. B., et al.: ATS 2011, P E71. 20 Wouters, E. F. M., et al.: J Clin Endocrinol Metab, 2012, 97 (9), s. E1720– –E1725.
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Atopický ekzém – co nového v léčbě? Prim. MUDr. Štěpánka Čapková Dermatologické oddělení pro děti, FN Motol, Praha RNDr. Dana Nováková Klinika nukleární medicíny a endokrinologie UK 2. LF a FN Motol, Praha 1 Paller, A. S. – Mancini, A. J.: Hurwitz clinical pediatric dermatology. Fourth edition multimedia on line. Elsevier Saunders, 2011, s. 624. 2 Bieber, T. – Cork, M. – Reitamo, S.: Atopic dermatitis: a candidate for disease-modifying strategy. Allergy, 2012, 67, s. 969–975. 3 Benáková, N.: Atopická dermatitida v roce 2009. Čes-slov Derm, 2009, 84, s. 65–86. 4 Baron, S. E. – Cohen, S. N. – Archer, C. B.: Guidance on the diagnosis and clinical management of atopic eczema. Clinical and Experimental Dermatology, 2012, 37, s. 7–12. 5 Akdis, C. A. – Akdis, M. – Bierber, T., et al.: Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinilcal Imunology / American Academy of Allergy,
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sthma and Immunology / PRACTALL Consensus Report. J Allergy Clin A Immunol, 2006, 118, s. 152–169. Ring, J. – Alomar, A. – Bieber, T., et al.: Guidelines for treatment of atopic eczema (atopic dermatitis) Part I. JEADV, 2012, 26, s.1045–1060. Ring, J. – Alomar, A. – Bieber, T., et al.: Guidelines for treatment of atopic eczema (atopic dermatitis) Part II. JEADV, 2012, 26, s. 1176–1193. Hoare, C. – Li Wan Po, A. – Wiliams, H.: Systematic review of tretments for atopic eczema. Health Technol Assess, 2000. Darsow, U. – Wollenberg, A. – Simon, D., et al.: ETFAD/EADV eczema task force 2009 position paper on diagnosis and treatment of atopic dermatitis. JEADV, 2010, 24, s. 317–328.
Kontaktní ekzém – kontaktní alergeny doc. MUDr. Eliška Dastychová, CSc. I. dermatovenerologická klinika LF MU a FN u sv. Anny v Brně 1 Beckmann, B. – Ippen, H.: Teebaum-Öl. Dermatose, 1998, 46, s. 120–124. 2 Camarasa, J. G.: Contact dermatitis to ketoprofen. Contact Dermatitis, 1985, 12, s. 120–122. 3 Cavelier, C. – Foussereau J.: Kontaktalergie gegen Metalle und deren Slze. Teil II. Nickel, Kobalt, Quecksilber und Palladium. Dermatosen in Beruf und Umwelt, 1995, 43, s. 152–162. 4 Coz, Ch. J. L. – Bottlaender, A. – Scrivener, J. N. – Santinelli, F. – Cribier, B. J. – Heid, E. – Grosshans, E. M.: Photocontact dermatitis from ketoprofen and tiaprofenic acid: Cross-reactivity sutdy in 12 consecutive patients. Contact Dermatitis, 1998, 38, s. 245–252. 5 Dastychová, E.: Nežádoucí účinky extern obsahujících ketoprofen. Čs Derm, 2000, 75, s. 51–55. 6 Dooms-Goossens, A. – Andersen, K. E. – Brandao, F. M. – Bruynzeel, D. – Burrows, D. – Camarasa, J. – Ducombs, G. – Frosch, P. – Hannuksela, M. – Lachapelle, J. M. – Lathi, A. – Menné, A. – Wahlberg, J. E. – Wilkinson, J. D.: Corticosteroid contact allergy: an EECDRG multicentre study. Contact Dermatitis, 1996, 35, s. 40–44. 7 Foussereau, J.: An epidemiological study of contact allergy to 5-chloro-3-methylisothiazolone 3-methyl-isothiazolone in Strasbourg. Contact Dermatitis, 1990, 22, s. 68–70. 8 Gebhardt, M. – Wollina, U.: Kutane Nebenwirkungen nichtsteroidaler Antiflogistika. Z Rheumatol, 1995, 54, s. 405–412. 9 Greig, J. E. – Thoo, S. L. – Carson, Ch. F. – Riley, T. V.: Allergic contact dermatitis following use of a tea tree oil hand-wash not due to tea tree oil. Contact Dermatitis, 1999, 41, s. 354. 10 Groot, A. C.: Airborne allergic contact dermatitis from Tea Tree Oil. Contact Dermatitis, 1996, 35, s. 304–305. 11 Groot, A. C. – Frosch, P. J.: Averse reactions to fragrances. A clinical review. Contact Dermatitis, 1997, 36, s. 57–86. 12 Kränke B.: Allergisierende Potenz von Teebaum-Öl. Hautarzt, 1997, 48, s. 203–204. 13 Lehmann, P. – Werner, A. – Bäuerle, G. – Breit, R. – Frosch, P. – Fuchs, T. – Günter, G. – Neumann, N. J. – Schaller, J. – Schulze-Dirks,
A. – Vieluf, D. – Wilhelm, P.: Coricosteroid contact dermatitis: Result of a multicenter study from the German Contact Allergy Group. Dermatosen, 1997, 45, s. 116–120. 14 Mozzanica, N. – Pigatto, P. D.: Contact and photocontact allergy to ketoprofen: Clinical and experimental study. Contact Dermatitis, 1990, 23, s. 336–340. 15 Rietschel, R. L. – Fowler, J. F., jr.: Fischer’s Contact dermatitis, 2008, s. 275–278, 287–288, 670–681, 393–404. 16 Semrádová, V. – Dastychová, E. – Navrátilová, Z.: Kontaktní alergie na kortikosteroidy. Čs Derm, 1999, 74, s. 113–117. 17 Semrádová, V. – Dastychová, E.: Polyvalent contact allergy to corticosteroids: A report of two cases. JEADV, 2001, 15, s. 350–353. 18 Urbanček, S.: Alergény štandardnej série. In: Urbanček, S. – Dastychová, E. – Buchvald, D. – Vocilková, A.: Kontaktné alergény v pracovnom a životnom prostredí, 2006, s. 41–73. 19 Uter, W. – Lessmann, H. – Geier, J. – Schnuch, A.: Contact allergy to ingredients of hair cosmetics in female hairdressers and clients — an 8-year analysis of IVDK data. Contact Dermatitis, 2003, 49, s. 236–240. 20 Uter, W. – Hegewald, J. – Aberer, W. – Ayala, F. – Bircher, A. J. – Brach, J. – Coenraads, P.-J. – Schuttellar, M.-L. A. – Elsner, P. – Fartasch, M. – Mahler, V. – Fortina, A. B. – Frosch, P. J. – Fusch, T. – Johansen, J. D. – Menné, T. – Jolanou, R. – Krêcisz, B. – Kiec-Swierczynka, M. – Larese, F. – Orton, D. – Peserico, A. – Rantanen, T. – Schnuch, A.: The European standard series in 9 European countries, 2002/2003 — First results of the European Surveillance Systém on Contact Allergies. Contact dermatitis, 2005, 53, s. 136–145. 21 Wilkinson, S. M.: Hypersensitivity to topical corticosteroids. Clin Exp Derm, 1994, 19, s. 1–11. 22 Wilkinson, S. M. – Hollis, S. – Beck, M. H.: Reaktionen auf andere Kortikosteroide bei Patienten mit allergischer Kontaktdermatitis infolge Hydrocortison. Z Hautkr, 1995, 70, s. 368–372. 23 The ESSCA Writing Group: The European Surveillance System of Contact Alleries (ESSCA): results of patch rating the standard series, 2004. JEADV, 2008, 22, s. 174–181.
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Léčba atopické dermatitidy v přehledu MUDr. Radek Litvik Kožní oddělení FN Ostrava 1 Litvik, R.: Atopický ekzém dospělého věku. In: Dermatologie v kazuistikách. Praha, Mladá fronta, 2008, s. 187–194. 2 Litvik, R.: Úloha kožní bariéry u atopické dermatitidy. Farmakoterapie, 2008, s. 11–21. 3 Proksch, E.: The role of emollients in the management of diseases with chronic dry skin. Skin Pharmacol Physiol, 2008, 21, s. 75–80. 4 Meibach, H. I. – Surber, Ch.: Topical Corticosteroids. Basel, Karger, 1992. 5 Litvik, R.: Tacrolimus v koncentraci 0,03 % a 0,1 % ve formě masti. Farmakoterapie, 2008, s. 5–10. 6 Simpson, E. L. – Hanifin, J. M.: Atopic dermatitis. J Am Acad Dermatol, 2005, 53, s. 115–128. 7 Hanifin, J. M. – Cooper, K. D., et al.: Guidelines of care for atopic dermatitis, developed in accordance with the American Academy of Dermatology (AAD)/American Academy of Dermatology Association “Administrative Regulations for Evidence-Based Clinical Practice Guidelines“. J Am Acad Dermatol, 2004, 50, s. 391–404. 8 Jung, T. – Stingl, G.: Atopic dermatitis: therapeutic concepts evolving from new pathophysiologic insights. J Allergy Clin Immunol, 2008, 122, s. 1074–1081.
9 Benáková, N.: Atopická dermatitida. In: Léčba atopické dermatitidy v novém milleniu. Praha, Astellas Pharma, 2005, s. 3–6. 10 Polášková, S.: Proč může selhat léčba u dětí s atopickou dermatitidou. Farmakoterapie, 2008, s. 32–35. 11 Barbaud, A., et al.: Interest in an emollient containing pentyl rhamnoside in the management of xerosis and atopic skin. Cosmetic Dermatology, 2008, 21, s. 647–651. 12 Cork, M. J., et al.: J Allergy Clin Immunol, 2006, 118, s. 3–21. 13 Leung, D. Y. M. – Soter, N. A.: J Am Acad Dermatol, 2001, 44 (dopl.), s. S1–12. 14 Cork, M., et al.: Dermatology Update. Montreal, Kanada, 6.–7. 11. 2003. 15 ISAAC Steering Committee: Lancet, 1998, 351, s. 1225–1232. 16 Bieber, T.: N Engl J Med, 2008, 358, s. 1483–1494. 17 Beattie, P. E. – Lewis-Jones, M. S.: Br J Dermatol, 2006, 155, s. 145–151. 18 Spergel, J. M.: Am J Clin Dermatol, 2008, 9, s. 233–244. 19 Cork, M. J., et al.: Epidermal barrier dysfunction in atopic dermatitis. In: Rawlings, A. V. – Leyden, J. J. (eds.): Skin Moisturization. London, Informa Healthcare, 2009 (v tisku).
Role vitaminu D u chronických zánětlivých onemocnění MUDr. Jana Čepová, Ph.D., MBA | MUDr. Margareta Beyerová | Ing. Eva Klapková, Ph.D. | Ing. Marta Pechová | prof. MUDr. Richard Průša, CSc. Ústav lékařské chemie a klinické biochemie, 2. LF UK a FN v Motole, Praha 1 Nevoral, J.: Cílený screening celiakie. Postgraduální medicína, 2010, 76, s. 452. 2 Kohout, P.: Celiakie. Postgraduální medicína, 2010, 82, s. 463–477. 3 Novotná, B.: Vitamin D – imunita, alergie a astma. Medical Tribune, 2012, 5. 4 Krejsek, J. – Kopecký, O.: Klinická imunologie. NUCLEUS HK, 2004. 5 Holick, M. F.: The Vitamin D solution. Hudson Street Press, USA, 2011. 6 Holick, M. F.: Vitamin D Deficiency. New Engl J Med, 2007, 357, s. 266–281. 7 IOF Releases New Position Statement on Vitamin D Reccommendations for Older Adults, Florencie, 2010, www.nutritionhorizon.com. 8 Čepová, J. – Kolářová, J. – Pechová, M. – Kotaška, K. – Průša, R.: Kazuistiky
z osteologické ambulance. Interní medicína pro praxi, 2012, 14, 2, s. 78–80. 9 Čepová, J. – Pechová, M. – Beyerová, M.: Kazuistiky z osteologické ambulance. Farmakoterapie – klinická praxe, 2012, 8. 10 Brouwer-Brolsma, E. M. – Bischoff-Ferrari, H. A., et al.: Vitamin D: do we get enough? Osteoporosis Int, 2012, s00198-012-2231-3. 11 Palička, V.: Vitamin D a jeho role (nejen) v osteologii. Interní medicína pro praxi, 2011, 13 (10), s. 383–387. 12 Raška, I.: Vitamin D v prevenci onemocnění? Medicína po promoci, 2012, 4. 13 Kvapil, M.: Diabetologie 2012. Triton, 2012. 14 Čepová, J.: Vitamin D ve zdraví a nemoci, 13. Bergmeyerova konference. Labor Aktuell, 2012, 2.
Doporučené postupy v léčbě astmatu bronchiale MUDr. Václava Bártů, Ph.D. Plicní oddělení, Medicon, a. s., Praha 1 Global Initiative for Astma (GINA). GINA workshop report: Global strategy for astma management and prevention. http://www.ginasthma.com. 2 Banks, E. D. – Jalloul, A.: Occupational astma, work-related astma and reactive airways dysfunction syndrome. Curr Opin Pulm Med, 2007, 13, s. 131–136. 3 Wenzel, S. E. – Covar, R.: Update in astma 2005. Am J Respir Crit Care Med, 2006, 173, s. 698–706. 4 Turner, S.: Exhaled nitric oxide in the diagnosis and management of astma. Curr Opin Allergy Clin Immunol, 2008, 8, s. 70–76. 5 Michils, A. – Baldassarre, S. – Van Muylem, A.: Exhaled nitric oxide and astma kontrol: A longidutinal study in unselected patiens. Eur Respir J, 2008, 31, s. 539–546.
6 Sutherland, E. R. – Martin, R. J.: Astma and Atypical Bacterial Infec tion. Chest, 2007, 132, s. 1962–1966. 7 Moore, W. C. – Peters, S. P.: Update in Astma 2006. Am J Respir Crit Care Med, 2007, 175, s. 649–654. 8 Tamesis, G. P. – Krawiec, M. E.: Heterogenity in response to astma medications. Curr Opin Allergy Clin Immunol, 2007, 7, s. 185–189. 9 Holgate, S. – Casale, T. – Wenzel, S. – Bousquet, J. – Deniz, Y. – Reisner, C.: The anti-inflammatory effects of omalizumab confirm the central role of IgE in allergic inflammation. J Allergy Clin Immunol, 2005, 115, s. 459–465. 11 Aubier, M. – Buhl, R. – Ekstrom, T. – Ostinelli, J. – van Schayck, C.P. – Selroos, O. – Haughney, J.: Comparison of two twice-daily doses of
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budesonide/formoterol maintance and reliever therapy. Eur Repir J, 2010, 36, s. 524–530. 11 Kašák, V.: Kontrola astmatu a exacerbací. Medicína po promoci, 2010, 11, s. 69–73.
12 Ekerljung, L. – Bossios, A. – Lotvall, J. – Olin, A. C. – Ronmark, E.: Multi-symptom asthma as an indication of disease severity in epidemiology. Eur Repir J, 2011, 38, s. 825–832. 13 Pauk, N.: Současný pohled na postavení LABA v terapii astmatu. Farmakoterapie, 2010, 6, s. 449–452.
Rinosinusitidy: od praktického lékaře do specializované péče ORL nebo alergologie? MUDr. Jan Pokorný, CSc. DG Centrum Ostrava, ORL 1 Markalous, B. – Charvát, F., et al.: Zobrazení hlavy. Triton, 2006, 658 s.
2 Kuchynková, Z.: Nosní polypy. Galén, 2003, 100 s.
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ACTA MEDICINAE 2/2013 ALERGOLOGIE, PNEUMOLOGIE Kompletní literatura