JMÉNO:
Jan Ženka, RNDr., CSc.
VZDĚLÁNÍ: 1974
GYMNÁZIUM SVITAVY, Svitavy
1979
PŘÍRODOVĚDECKÁ FAKULTA UJEP, Brno, obor biochemie
1980
RNDr.
1984
CSc., obor biologie. Kandidátská disertační práce: Antigenní vlastnosti enzymů. Použití enzymů jako antigenů v imunodiagnostice.
VĚDECKÁ KARIERA: 1980 – 1984
VĚDECKÝ PRACOVNÍK. Oddělení aplikované helmintologie, Parazitologický ústav ČSAV, České Budějovice
1984 - 1995
VĚDECKÝ PRACOVNÍK. Oddělení aplikované helmintologie, Parazitologický ústav ČSAV, České Budějovice
1986 – 1988
VĚDECKÝ TAJEMNÍK. Oddělení aplikované helmintologie, Parazitologický ústav ČSAV, České Budějovice
2005 – 2015
VEDOUCÍ LABORATOŘE. Laboratoř genomiky, Společné pracoviště BC AV ČR, v.v.i. a PřF JU, České Budějovice
2006 – dosud
VĚDECKÝ PRACOVNÍK. Katedra medicínské biologie Přírodovědecké fakulty Jihočeské univerzity
PEDAGOGICKÁ ČINNOST: 2005 -2007
ZDRAVOTNĚ SOCIÁLNÍ FAKULTA JU, České Budějovice: Biochemie a biofyzika nukleových kyselin, Metodologie vědeckého výzkumu
2006- dosud
PŘÍRODOVĚDECKÁ FAKULTA JU, České Budějovice: Metody preklinického výzkumu terapie nádorových onemocnění pro bakaláře. Preklinický výzkum terapie nádorových onemocnění pro magistry. Vedení bakalářských a magisterských prací
JAZYKY:
Česky, anglicky, německy, rusky
PUBLIKACE: PUVODNÍ PRÁCE:
Zenka J., Prokopic J., 1983: Activities of some enzymes in the perienteric fluid of Ascaris suum. Folia parasitol. 30: 373-376. Zenka J., Prokopic J., 1984: Isolation and properties of alpha-amylase from perienteric fluid of Ascaris suum. Folia parasitol. 31: 183-186. Zenka J., Prokopic J., 1985: Aminopeptidase inhibitor from Ascaris suum. Folia parasitol. 32: 247-253. Zenka J., Prokopic J., 1986: Study of cytochromes from mitochondria of Taenia crassiceps (Zeder, 1800) cysticerci. Folia parasitol. 33: 145-148. Zenka J., Prokopic J., 1986: Study of the properties of alkaline phosphatase in Taenia crassiceps (Zeder, 1800) cysticerci. Folia parasitol. 33: 281-284. Zenka J., Prokopic J., 1986: Contribution to the knowledge of aerobic processes in Taenia crassiceps larvae (Zeder, 1800). Folia parasitol. 33: 331-336. Zenka J., Prokopic J., 1987: Malic enzyme, malate dehydrogenase, fumarate reductase and succinate dehydrogenase in the larvae of Taenia crassiceps (Zeder, 1800). Folia parasitol. 34: 131-136.
Zenka J., Kopacek P., Vokurkova N., 1987: Studies on the properties of malic enzyme and malate dehydrogenase from Taenia crassiceps (Zeder, 1800) cysticerci. Folia parasitol. 34: 323-328. Zenka J., Prokopic J., 1987: Characteristics of malic enzyme from the cysticerci of Taenia crassiceps (Zeder, 1800). Folia parasitol. 34: 233-241. Zenka J., Prokopic J., 1988: Transhydrogenase activities in the mitochondria of Taenia crassiceps (Zeder, 1800) cysticerci. Folia parasitol. 35: 31-36. Zenka J., Prokopic J., 1989: Purification and properties of cytoplasmic malate dehydrogenase from Taenia crassiceps (Zeder, 1800) cysticerci. Folia parasitol. 36: 59-65. Glamazdin I.G., Zenka J., Lukes.S., Kopacek P., Safarik I., 1988: Ispolzovanije geterologičnych antigennov iz ličinok Taenia crassiceps v immunodiagnostike bovisnogo cisticerkoza s pomoščju immunofermentnoj reakciji. Bull VIGIS 52:xx-xx. Hulinska D., Grim M., Vojtisek M., Zenka J., 1989: Regeneration in mouse skeletal muscle injured by Trichinella larvae. Folia parasitol. 36: 185-190. Zenka J., Hulinska D., Jegorov A., 1989: An analysis of Trichinella pseudospiralis excretions and study of their effect on striated muscles of mouse. Folia parasitol. 36: 177-183. Giboda M., Zenka J., Julis I., Vitovec J., Zdarska Z., 1992: Modification of tissue egg load in schistosomiasis mansoni as a tool for morbidity reduction. Mitt. Osterr. Ges. Tropenmed. Parasitol. 14: 89-96. Zdarska Z., Giboda M., Zenka J., 1992: The ultrastructure of the Schistosoma mansoni egg: the line of hatching. Helminthologia 29: 63-65. Giboda M., Zenka J., Julis I., Vitovec J., 1992: Experimental schistosomiasis mansoni: modulation of granuloma by inhibition of collagen cross-links formation. Preliminary report. Annals of Tropical Medicine and Parasitology 86: 631-636. Zenka J., Hulinska D., Allen R.E., Skarli M., Pokorny T., Jindrova H., Hermanek J., Kudweis M., 1993: An attempt to explain regeneration of striated muscles injured by Trichinella pseudospiralis larvae. Helminthologia 30: 35-40. Zenka J., Jegorov A., 1993: Substrate specificity of fumarate reductase activity of Taenia crassiceps mitochondria. International Journal for Parasitology 23: 959-960. Zenka J., 1993: Taenia crassiceps: mitochondrial succinate dehydrogenase and fumarate reductase activities. Rivista di Parassitologia 54: 431-435.
Nemec V., Zenka J., 1996: Activity of phosphatases and esterases in the aphid, Acyrthosiphon pisum (Hemiptera: Sternorrhyncha: Aphididae), and in the gut wall of Galleria mellonella (Lepidoptera: Pyralidae) larvae and pupae. Eur. J. Entomol. 93: 37-44. Kaiserová P., Kalferstová L., Maršíková H., Bartoňová I., Koník P., Kopecký J., Ženka J., 2014: Proenzyme therapy of sarcoma S-180 and melanoma B16-F10. J Appl Biomed 12(1): 39-47. Janotová T., Jalovecká M., Auerová M., Švecová I., Bruzlová P, et al., 2014: The Use of Anchored Agonists of Phagocytic Receptors for Cancer Immunotherapy: B16-F10 Murine Melanoma Model. PLoS ONE 9(1): e85222.doi:10.1371/journal.pone.0085222
PUBLIKOVANÁ ABSTRAKTA:
Zenka J., Lukeš S., 1985: Pouziti purifikovanych antigenu v diagnostice experimentalnich cestodoz a jejich vlastnosti. IV. Kongres ceskoslovenskych imunologu, Nitra, Sbornik souhrnu, p. 41. Zenka J., Prokopic J., 1985: Malic enzyme, malate dehydrogenase, fumarate reductase and succinate dehydrogenase in Taenia crassiceps larvae (Zeder, 1800). The Second International Symposium "Taeniasis/Cysticercosis and Echinococcosis/Hydatidosis , Ceske Budejovice, Proceedings, pp. 401-410. Zenka J., Prokopic J., 1985: Contribution to the knowledge of aerobic processes in Taenia crassiceps larvae (Zeder, 1800). The Second International Symposium "Taeniasis/Cysticercosis and Echinococcosis/Hydatidosis , Ceske Budejovice, Proceedings, pp. 411-418. Zenka J., 1986: Some properties of pyridine nucleotide transhydrogenases in the mitochondria of Taenia crassiceps larvae. Vth International Helminthological Symposium Helminths, Helminthoses, Environment , Strbske Pleso, Abstracts of reports, p. 82. Hulinska D., Zenka J., Grim M., Jegorov A., 1987: Immunocytochemical study of Trichinella spiralis and T. pseudospiralis and effect of their excretion on the muscle fibre alterations. Histochemical Journal 19: 606, Abstracts of the Annual Symposium of the Czechoslovakian Society of Histochemistry and Cytochemistry, Harrachov. Hulinska D., Zenka J., Jegorov A., 1987: Vliv Trichinella pseudospiralis a jejich exkretu na regresi a regeneraci pricne pruhovanych svalovych vlaken mysi. Aktualne otazky humannej parazitologie, Bratislava, Abstrakta pp. 54-55.
Zenka J., Jegorov A., 1988: Succinate dehydrogenase and fumarate reductase activities in mitochondria from cysticerci of the tapeworm Taenia crassiceps (Zeder, 1800). 14th International Congress of Biochemistry, Praha, Abstracts, p. 111. Zenka J., Prokopic J., 1988: Contribution to answering the question whether the specific position of malate dehydrogenase in anaerobic catabolism of saccharides in helminths is related to specific kinetic parameters of this enzyme. V. EMOP , Budapest, Abstracts p. 173. Lukes, S., Zenka J., Glamazdin I.G., 1988: Spolecne antigeny tasemnic rodu Taenia. V.Kongres ceskoslovenskych imunologu, Plzen, Abstracts, p. 80. Lukes, S., Zenka J., Glamazdin I.G., 1989: Comparative analysis of cysticercus antigens of various Taenia species in relation to specific serodiagnosis of bovine cysticercosis. 13th Conference WAAVP, Berlin, Abstracts, p. 65. Zenka J., Jegorov A., 1989: Fumarat reduktazova aktivita u parazitickych cervu. Parazitozy hospodarskych zvirat, Ceske Budejovice, Proceedings, pp. 166-170. Giboda M., Zenka J., Julis I., Vitovec J., 1991: Schistosoma mansoni: Modulation of granuloma formation. Czech and Slovak Conference of Tropical Medicine, Infectious Diseases and Antiinfectious Therapy with International Participation, Piestany, Abstracts, p. 109. Zdarska Z., Giboda M., Zenka J., 1991: Schistosoma mansoni egg: Ultrastructure of the future line of hatching rupture. Conference of Tropical Medicine, Infectious Diseases and Antiinfectious Therapy with International Participation, Piestany, Abstracts, p. 110. Zenka J., Fioravanti C.F., 1991: Properties of NADH:NAD+ transhydrogenase and lipoamide dehydrogenase in the mitochondria of Hymenolepis diminuta and Taenia crassiceps. 6th International Helminthological Symposium, The High Tatras, Abstracts p. 75. Giboda M., Zdarska Z., Zenka J., 1992: Ucinok praziquantelu na vajicka Schistosoma mansoni v experimente. Aktualne otazky humannej parazitologie, Bratislava, Abstracts pp. 39-40. Zenka J., Jegorov A., 1992: Substratov specificita fumarat reduktazove aktivity mitochondrii Taenia crassiceps. XIII. Celostatni biochemicke dny, Ceske Budejovice, Abstracts p. 91. Dubinsky P., Zenka J., 1992: Biochemie helmintu. 1. helmintologicke dny, Dolni Vestonice. Trnka F., Ženka J., 2002: Biologické pojetí kancerogeneze a terapie maligních novotvarů. Rekonstrukce historické hypotézy. SVU News 4: 11.
Beranová E., Klouda K., Zeman K., Máchová J., Ženka J., Danihelka P., 2010: Radioprotective properties and toxicity tests of C60 fullerene derivatives in vivo & in vitro. NANOCON 2010, Olomouc, Conference Proceedings, pp.251-262. Živná V., Ženka J., 2011: Studium vlivu BAF® na myší melanom B16-F10 a sarkom S-180. Sborník k semináři společnosti Areko® “Výzkum BAF® 2010“, Praha, pp. 10-13. Kaiserova P., Kalferstova L., Marsikova H., Kopecky J., Zenka J., 2011: (Pro)enzyme therapy of sarcoma S-180 and melanoma B16-F10. Poster presentation. EMBO Conference “Homeostasis and perturbations of immunity”, Capo Caccia, Sardinia, Italy. Slaninová J., Monincová L., Ženka J., Turánek J., Čerovský V., 2012: Application possibilities of antimicrobial peptides from wild bees. Peptide Therapeutics Conference, Lanzarote, Abstract Booklet. Caisova V., Vieru A., Kumzakova Z., Glaserova S., Husnikova H., Vacova N., Kopecky J., Zenka J. 2015: The use of anchored agonists of phagocytic receptors for effective cancer. immunotherapy. 4th European Congress of Immunology, Vienna, Abstract Book, p. 373. Caisova V., Vieru A., Kumzakova Z., Glaserova S., Husnikova H., Vacova N., Kopecky J., Zenka J. 2015: The use of anchored agonists of phagocytic receptors for effective cancer immunotherapy. XI. Diagnostic, Predictive and Experimental Oncology Days (December 23, 2015), Olomouc. Zenka J. 2016: Innate immunity based cancer immunotherapy. 1st Annual BioSpot Conference, Prague, Abstract Book, p. 7.
PATENTY: Zenka J., Hulinska D., Holusa R., Pokorny T., Jegorov A., 1992: Preparation of the improvement of the regenerative process of injured striated muscles. U.S. Patent No. 5,096,930
