88
DAFTAR PUSTAKA Ackers R. G., D. Moss, B.E. Picton, S.M.K. Stone and C.C. Morrow. 2007. Sponges of The British Isles (“Sponge V”) A Colour Guide and Working Document. Marine Conservation Society. Belfast. Alluri, LH., Thameemulansari., and C. UmaMaheswara, Reddy. 2012. Cytotoxic Activity of Methanol and Dichloromethane Extracts Soft Halicona Species. Sri Ramachandra College of Pharmacy, Sri Ramachandra University, Chennai, Tamil Nadu, India. Vol. 3 (6): 1782-1784. (ISSN: 0975-8232). Amalia. N.L.2008. Uji Sitotoksik Ekstrak Etanol 70 % Buah Merica Hitam (Piper nigrum L.) Terhadap Sel Hela. (makalah). Surakarta: Universitas Muhammadiyah Surakarta. Amir, I. 1992. Sponge Fauna of Coral Reef Ecosystem in The Seribu Islands and Ujung Kulon. In Third ASEAN Science and Technology Week Conference Proceedings. Vol.6. Marine Science Living Coastal Resources. Amir, I., Budiyanto, A. 1996. Mengenal Spons Laut (Demospongiae) Secara Umum. Oceana, 21, (2) :, 15-31. Anwar, C. 1994. Pengantar Praktikum Kimia Organik. FMIPA Universitas Gajah Mada: Yogyakarta. Apantaku, L. M. 2002. Breast-Conseving Surgery for Breast Cancer. Am. Fam. Physician 66 (12) : 2271-2278. Astuti, P., Alam, G., Hartati, M. S., Sari, D., dan Wahyuono, S. 2005. Uji Sitotoksik Senyawa Alkaloid dari Spons Petrosia sp: Potensial Pengembangan sebagai Antikanker. Majalah Farmasi Indonesia 16 (1). Begmann, W. and Feeney, R.J. 1951. Contributions to The Study of Marine Products. The nucleosides of sponges. J. Org. Chem. 16 : 981-987. Calabresi, P., and Chabner, B. 1991. In: Gilman, G.E., Rall, T. W., Taylor, O., (Eds). The Pharmacological Basics of Therapeutis, 8th, ed., 1202-1290. Pergamon Press, USA. Cao, S. G., Valerie, H.L., Wu, X.H., Sim, K.Y., Tan, B.H.K., Pereira, J.T., and Goh, S.H. 1998. Novel Cytotoxic Polyprenylated Xanthones from Garcinia gaudichaudii. Tetrahedron, 54 : 10915-10924. Carballo, J.L., Hernandez Inda, Z.L., Perez, P., Garcia Gravaloz, M.D. 2002. Comparison Between Two Brine Shrimp Assays to Detect in vitro Cytotoxicity in Marine Natural Products. BMC Biotechnology. Vol. 2 : 1472-6570.
88
89
Chairman K, R. Singh AJA, Alagumuthu G. 2012. Cytotoxic and Antioxidant Activity of Selected Marine Sponges. Asian Pac J Trop 2(2) : 234-238. Chakrabarti O and Krishna S. 2003. Molecular Interaction of High Risk Human Papillomavirus E6 and E7 Oncoproteins: Implications for Tumor Progression. Journal of Biosciences. 28 (3) : 337-348. Conception, G.P. 1995. in Bioinformatics and Biotechnology. GeneSeas Asia inc., Manila Philippines. Cragg, G.M., Newman, D. J., Weiss, R.B. 1997. Coral Reefs, Forests, and Thermal vents: The Worldwide Exploration of Nature for Novel Antitumor Agents. Semin Oncol., 24 : 156-163. Cram, W.R., Stewart, C.F., In; Herfindal, E.T., Gourley, A.B., and Hart, L.L., (Eds). 1992. Clinical Pharmacy and Therapeutics, 5th ed., 271-290, Maryland USA: Williams and Wilkins. Creswell, J. 1982. Analisis Spektrum Senyawa Organik Alih Bahasa Kosasih Padmawinata. Bandung : ITB. Dahuri, R. 2003. Keanekaragaman Hayati Laut. Jakarta : Penerbit PT Gramedia Pustaka Utama. Diananda, Rama. 2007. Mengenal Seluk Beluk Kanker. Jogjakarta: Katahati. Doyle, A, dan Griffiths, JB. 2000. Cell and Tissue Culture for Medical Research. New York: John Wiley and Sons Ltd. Erickson, Karen L., John A, Beutler., John H, Cardellina II, and Michael R, Boyd. 1997. Salicylihalamides A and B, Novel Cytotoxic Macrolides from the Marine Sponge Haliclona sp. J. Org. Chem. 62 (23) : pp 8188-8192. Fajarningsih, ND., Januar HI., Nursid M., dan Wikanta T., 2006. Potensi Antitumor Ekstrak Spons Crella papilata Asal Taman Nasional Laut Kepulauan Seribu. Jurnal Pasca Panen dan Bioteknologi Kelautan dan Perikanan. Vol. 1 (1): 35-42. Faulkner, D.J., Unson, M.D., and Bewley, C.A. 1994. The Chemistry of Some Spons and Their Symbionts. Pure & Appl. Chem., 66 : 1883 – 1990. Faulkner, D.J. 1998. Marine Natural Products. Natural Product Report, Vol. 15: 113-158. Foster, M.P., G. P, Concepcion., G.B, Caraan., CM, Ireland. 1992. Study of Sponges and Ascidians. J.Org. Chem. 57: 6672-6675. Freshney, RI. 1992. Animal Cell Culture. Practical Approach. Second Edition. Oxford New York: Oxford University Press.
90
Garson, M. J. 1994. The Biosynthesis of Secondary Metabolits: Why is Important. In: Sponss in Time and Space, edited by R. W. M. Van Soest, Th. M. G. Van Kempen and J. C Braekman (eds.)., Proceeding 4th International Porifera Conggress, Amsterdam/Netherland, : 428-429, Green D., Tew, K.D., Hisamatsu, T., and Schein, P.S. 1982. Correlation of Nitrosourea Murine Bone Marrow Toxicity with Deoxyribonucleic Acid Alkylation and Chromatin Binding Sites. Biochem. Pharmacol., 31 : 16711679. Gritter, Bobbit dan Schwarting. 1991. Pengantar Kromatografi. Terjemahan Kosasih Padmawinata. Bandung : ITB. Haefner, B. 2003. Drag from the deep: marine natural products drug candidates. Drug Disc. Today. 6 (12): 536-544. Hanani, Endang, Abdul Mun’im, Ryany Sekarini. 2005. Identifikasi Senyawa Antioksidan dalam Spons Callyspongia sp dari Kepulauan Seribu. Majalah Ilmu Kefarmasian, Vol. II, No.3, Desember 2005 : 127-133 (ISSN : 16939883). Harborne, J. B. 1987. Metode Fitokimia: Penuntun Cara Modern Menganalisis Tumbuhan, Terjemahan Kosasih Padmawinata dan Iwang Soediro. Terbitan kedua. Bandung : ITB. Harper, M.K., T.S, Bugni., B.R, Copp., R.D, James., B.S, Lindsay., A.D, Richardson., P.C, Schnabel., D, Tasdemir., R.M, Van Wagoner., S.M, Verbitski., and C.M, Ireland. 2001. Introduction to The Chemical Ecology of Marine Natural Product. In: Marine Chemical Ecology (James B. McClintock & Bill J. Baker Eds.) CRC Press USA : 3-29. Herzig R.H., Hines, J.D., and Herzin, G.P. 1987. Cerebellar Toxicity with Highdose Cytosine Arabinoside. J. Clin. Oncol., Jun 1, 927-932. Hussain, S., Sheeba, F., Saba, A., Sajid, K. 2011. Marine Natural Products: A Lead for Anti-cancer. Indian Journal of Geo-Marine Sciences, Vol. 41 (1), Februari 2012 : 27-39. Iradjajanegara dan Wahyudi, Priyo. 2010. Uji Sitotoksisitas Ekstrak Etanol Herba Ceplukan (Physalis angulata) terhadap Sel T47D secara invitro. Jurnal Ilmu Kefarmasian Indonesia Edisi April 2010, Vol. 8, No. 1 : 41-47. Jimeno, J. M. 2002. A Clinical Armamentarium of Marine Derived Anti-Cancer Compounds. Anticancer Drugs, 13(suppl 1): S15 – 19. Pomponi S A. Jha, R.K and Zi-rong, X. 2004. Biomedical Compounds from Marine Organism. Marine Drugs, 2: 123 – 146.
91
Kamuhabwa, A., Nshimo, C., dan de Witte, P. 2000. Cytotoxicity of Some Medicinal Plant Extracts Used in Tanzanian 12 Tradisional Medicine. J. Ethnopharmacol. 70 : 143-149. Khopkar, S.M. 2003. Konsep Dasar Kimia Analitik. Diterjemahkan oleh A. Saptorahardjo. Jakarta: UI-Press Kintoko, Azimahtol Hawariah and Lope Pihie. 2008. Efek Antiproliferasi Ekstrak Kloroform Dari Phaleria macrocarpa (Scheff) Boerl. Pada Titisan Sel Kanker Manusia Rev. Universiti Kebangsaan Malaysia: Serdang. Kobayashi M., dan Rachmaniar R. 1999. Overview of Marine Natural Product Chemistry. Prosidings Seminar Bioteknologi Kelautan Indonesia I ’98. Jakarta 14-15 Oktober 1998: 23-32. Lembaga Ilmu Pengetahuan Indonesia. Krishna, G., dan Makoto H. 2000. In Vivo Rodent Micronucleus Assay: Protocol, Conduct and Data Interpretation. Journal of Elsevier Science. Vol. 455 : 155-166. Kumar, P. Praveen, S. Kumaravel and C. Lalitha. 2010. Screening of Antioxidant Activity, Total Phenolic and GC-MS Study of Vitex Negundo. African Journal of Biochemistry Research Vol. 4(7) : pp. 191-195. Available online at http://www. Academicjournals.org/AJBR. ISSN 1996-0778 ©2010. Lorgan, P.C., Crasey, T., and Coleman, R.E. 1996. Drugs. 51 : 571-584. Maruthupandian, A. and V. R. Mohan. 2011. GC-MS analysis of some bioactive constituen of Pterocarpus marsupium Roxb. International Journal of ChemTech Research CODEN (USA): IJCRGG ISSN : 0974-4290. Vol. 3, No. 3 : 1652 – 1657. Mclaughlin, J.L. 1991. Crown Gall Tumour on Potato Disc and Brine Shrimp Lethality: Two Simple Bioassay for Higher Plant Screening and Fractionation. Methods in Plant Biochemistry. Vol 6: 1-9. Meyer, B. N, Ferrigni, N. R, and Mclaughlin. 1982. Brine Shrimp: A Convenient General Bioassay for Active Plant Constituents. Journal of Planta Medical Research, Volume 45 :31-34. Motomasa, K. 1998. Search for Biologically Active Substances from Marine Sponges. In: Prosiding Seminar Bioteknologi I (R. R. eds.). Puslit Oseanologi LIPI: Jakarta. Mudianta, I. W, Tina SA, Katherine TA, Rohan AD, Hadi TA, Patricia YH, and Mary JG. 2012. Psammaplysin Derivatives from the Balinese Marine Sponge Aplysinella strongylata. Journal of Natural Products. 75: 2132 – 2143.
92
Muliani., Suryati E., Tompo A., Parenrengi A., Rosmiati. 1998. Isolasi Bioaktif Bunga Karang sebagai Fungisida pada Benih Udang Windu Penaeus monodon. Jurnal Penelitian Perikanan Indonesia. Vol IV, No. 2. Muniarsih, T., dan Rachmaniar, R. 1999. Isolasi Substansi Bioaktif Antimikroba dari Spons Asal Pulau Pari Kepulauan Seribu. Prosidings Seminar Bioteknologi Kelautan Indonesia I ’98. Jakarta 14-15 Oktober 1998: 151158. Lembaga Ilmu Pengetahuan Indonesia Jakarta. Munro MHG, Luibrand RT, and Blunt JW. 1989. The Search for Antivaral and Anticancer Compounds from Marine Organisms. Bioorganic Marine Chemistry. Volume 1. Springer-Verlag : 94-176. Murniasih, Tutik. 2005. Sustansi Kimia untuk Pertahanan Diri dari Hewan Laut Tak Bertulang Belakang. Oseana, Vol. 2 : 19-27. NCI. 2004. Scientists Establish Database of Genes Associated With Cancer Drug Resistance. Progress Report 2003. http//www.cancer.gov. Diakses pada tanggal 20 Pebruari 2014. Noorwati, S. 2007. Kemoterapi, Manfaat dan Efek Samping. Jakarta : Dharmais Cancer Hospital: Nunes, Bruno S., Felix D, Carvalho., Lucia M, Guilhermino., and Gilbert Van Stappen . 2006. Use of The Genus Artemia In Ecotoxicity Testing. Science Direct Environmental Pollution. 144 : 453-462. Nursid M, Wikanta T., Fajarningsih, N.D., Marraskuranto, E. 2006. Aktivitas Sitotoksik, Induksi Apoptosis dan Ekspresi Gen p53 Fraksi Metanol Spons Petrosia cf, nigricans Terhadap Sel Tumor HeLa. Jurnal Pascapanen dan Bioteknologi Kelautan dan Perikanan. Vol.1, No. 2, Desember1 : 03- 1 10. Nybakken, J. W. 1993. Marine Biology, Third Edition, Harper Collins College Publisher. Priyanto. 2007. TOKSISITAS (Obat, Zat Kimia, dan Terapi Antidotum). LESKONFI : Jakarta Barat. Proksch, P., Ebel, R., Edrada, R. A., Schupp, P., Lin, W. H., Sudarsono, Wray, V. and Steube, K. 2003. Detection of Pharmacologically Active Natural Products Using Ecology, Selected Examples from Indopacific Marine Invertebrates and Spons-Derived Fungi. Pure Applied Chem. 75: 343-352. Rashid, Mohammad., Kirk R, Gustafson., and Michael R, Boyd. 2001. A New Isoquinoline Alkaloid from the Marine Sponge Haliclona Species. J. Nat. Prod, 64 (9) : 1249-1250. Rasyid, Abdullah. 2009. Senyawa-senyawa Bioaktif dari Spons. Oseana, Vol. XXXIV, No. 2.
93
Riono, Y. 1999. Kanker Leher Rahim. Australia: Dept of Surgery Holywood Hospital. Hal 1-4. Rita W. S., et al. 2008. Isolasi dan Identifikasi Senyawa yang Berpotensi sebagai Antitumor Pada Daging Buah Pare (Momordica charantia L.). Jurusan Kimia FMIPA Universitas Udayana, Bukit Jimbaran. Jurnal Kimia.Vol. 2. Rizwan K., M. Zubair, N. Rasool, M. Riaz, M. Zia-UI-Haq, and V. de Feo. 2012. Phytochemical and Biological Studies of Agave attenuate. International Journal of Molecular Sciences, Vol. 13, No. 5 :6440-6451. Romimohtarto, K., dan Juwana, S. 2001. Biologi Laut: Ilmu Pengetahuan Tentang Biota Laut. Pusat Penelitian dan Pengembangan Oseanologi LIPI: Jakarta. Rosmiati dan Suryati. 2001. Isolasi Identifikasi dan Pengaruh Senyawa Bioaktif Spons Callyspongia pseudoreticulata terhadap Bakteri Patogen dari Udang. Jurnal Bioteknologi Pertanian, Vol. 6, No. 1, Balai Penelitian Perikanan Pantai Maros: Indonesia. Sastroamidjojo, H. 1991. Kromatografi. Liberty: Yogyakarta. Scheffner M, Huibregtse JM, Vierstra R and Howley PM. 1993. The HPV-16E6 and E6-AP Complex Functions as a Ubiquitin-protein Ligase in the Ubiquitination of p53. Cell. 75 : 495 – 505. SchmittE, Paguet C, Beauchemin M, and Bertrand R. 2007. Review: DNAdamage Response Network at the Crossroads of Cell Cycle Checkpoints, Cellular Senescence and Apoptosis. Journal of Zhejiang University Science B. 8(6) : 377 – 397. Sharrer, T. 2006. Hela Herself. The Scientist 20 (7) : 22. Silverstein, Robert M., G. Clayton Bassler, Terence C. Morrill. 1986. Penyidikan Spektrometrik Senyawa Organik. Alih bahasa A.J. Hartomo dan Any Victor Purba. Jakarta: Erlangga. Siswandono, dkk. 1995. Kimia Medisinal. Surabaya : Airlangga University Press. Hal : 407-426. Setyowati, E., Anggara, U., Sudarsono, Kardono, B., Rahmat, R., dan Meiyanto, E. 2007. Isolasi Senyawa Sitotoksik Spons Kaliapsis. Majalah Farmasi Indonesia, 18 (4) : 183-189. Soest, RWM Van, and Braekman JC. 1999. Chemosystematics of Porifera: A Review. Memoir of The Queensland Museum 44: 569-589. Sudha dan Masilamani S.. 2012. Characterization of Cytotoxic Compound from Marine Sediment Derived Actinomycete Streptomyces avidinii strain SU4. Asian Pac J Trop Biomed 2012; 2(10) : 770-773.
94
Sudjadi. 1992. Metode Pemisahan. Fakultas Farmasi UGM: Yogyakarta. Sukardiman., Wiwied Ekasari., Pharmasinta Putri Hapsari. 2006. Aktivitas Antikanker dan Induksi Apoptosis Fraksi Kloroform Daun Pepaya (Carica papaya L) terhadap Kultur Sel Kanker Mieloma. Media Kedokteran Hewan. 22 (2). Suryati E., Parenrengi A., dan Rosmiati. 2000. Penapisan serta Analisis Kandungan Bioaktif Sponge Clathria sp. yang Efektif sebagai Antibiofouling pada terifit (Balanus amphitrit). Jurnal Penelitian Perikanan Indonesia. Vol. V, No. 3. Stahl, E. 1985. Analisis Obat Secara Kromatografi dan Mikroskopi. Institut Teknologi Bandung: Bandung. Steven, Colegate dan Russel. 1993. Detection, Isolation. And Structural Determination. Albany California: Crc Press London Tokyo. Still, Clark., Kahn, M., and Mitra, A., 1978. Rapid Chromatographuc Technique for Preparatives Separations with Moderate Resolution. Journal of Organic Chemistry, Vol. 43. No. 14. Swantara, I M. D. 2005. Teknik Isolasi Senyawa Bioaktif dalam Tumbuhan, Workshop Pengelolaan Potensi Biodiversitas, Universitas Udayana, Bukit Jimbaran. Swersey, J.C. 1988. in Biomedical Importance of Marine Organisms D.G. Fautin, Ed., California Academy of Sciences, San Francisco. Tanaka, J., Agus, Trianto., Musri, Musman., Hammad H, Issa., Ikuko I, Ohtani, Toshio, Iciba., Tatsuo Higa., Wesley Y, Yoshida., and Paul J, Scheuer. 2002. New Polyoxygenated Steroids Exhibiting Reversal of Multidrug Resistance from the Gorgonian Isis Hippuris, Tetrahedron. 58: 6259-6266. Tarman, Kustiariyah. 2012. Pengembangan Protein Antikanker dari Kapang Endofit Indigenous Laut Indonesia Xylaria psidii KT30. Prosiding InSINas. Bogor: IPB. Tjay, Tan Hoan dan Rhardja, Kirana. 2002. Obat-obat Penting Edisi Kelima. Dirjen POM. Departemen Kesehatan RI. PT. Elex Media Komputindo: Jakarta. Trianto, A., Ambariyanto. 2005. Isolasi Senyawa Antikanker Leukemia dari Sponge Agelas nakamurai dan Haliclona sp. Fakultas Perikanan dan Ilmu Kelautan, Universitas Diponegoro.
95
Weerapreeyakul N, Nonpunya A, Barustux S, Thitimetharoch T, Sripanidkulchai B. 2012. Evaluation of the anticancer potential of six herbs against a hepatoma cell line. Chinese Med. 7(15) : 1-7. WHO.
2013. Human Papilloma Virus (HPV) and Cervical Cancer. http://www.who.int/mediacentre/factsheets/fs380/en. Diakses pada tanggal 20 Maret 2014.
Wilson A.P. Cytotoxicity and Viability Assays. Dalam JRW Masters, ed. Animal Cell Culture : A Practical approach,3rd ed. 2000. Oxford: Oxford University Press. Yoke K. Y, J.J. Tan, S.S. The, S.H. Mah, Gwendoline C.L, H.S Chiong and Z. Ahmad. 2012. Clinacanthus nutans Extracts are Antioxidant with Antiproleferative Effect on Cultured Human Cancer Cell Lines. Department of Biomedical Science. Universitas Putra Malaysia.
